PubMed Health⌕ Search

Biomedical subjects

E Lance

Publications and source records attributed to E Lance.

6 recordsLinked to original sources
PubMed1993

Prior lateral patellar dislocation: MR imaging findings.

PURPOSE: To illustrate the constellation of magnetic resonance (MR) findings that suggest prior patellar dislocation. MATERIALS AND METHODS: A computer search of all MR examinations of the knee with a coded diagnosis of patellar dislocation performed between February 1988 and October 1990 disclosed 22 cases (11 male and 11 female patients, aged 1-70 years). RESULTS: Eighteen cases (82%) demonstrated hemarthrosis, medical retinacular disruption, and contusion of the lateral femoral condyle. In 11 cases, the patella was displaced from the trochlear sulcus, but in no patient was there complete dislocation at the time of imaging. Axial short-inversion-time inversion-recovery (STIR) images demonstrated subtle subchondral and cancellous signal intensity abnormalities that were often poorly appreciated on T2-weighted images. In 11 cases, patellar dislocation was not suspected before MR imaging. CONCLUSION: Hemarthrosis, medial patellar and lateral femoral contusion, and retinacular disruption suggest prior lateral patellar dislocation. Because of its sensitivity to subtle intraosseous signal abnormality, axial STIR imaging is a valuable adjunct in the evaluation of the acutely injured knee.

Contusions↗
PubMed1991

Reaction of antibody to mycobacterial 65 kDa heat-shock protein with human chondrocytes.

We report on the reactivities of four monoclonal antibodies generated against mycobacterial proteins to human chondrocytes, cells in cartilage which may be subject to immune attack in rheumatoid arthritis. Only one of the monoclonal antibodies, ML30, which had been shown previously to react with a human homologue to heat-shock protein (hsp), reacted strongly to chondrocytes. By immunocytochemical methods using fixed chondrocytes, ML30 reacted to cytoplasmic constituents in a granular pattern. There were no marked qualitative differences in the staining intensities and patterns of chondrocytes kept at ambient temperatures and those subjected to 42 degrees C heat treatment. No significant staining was observed with normal peripheral blood mononuclear cells. By indirect immunofluorescence, the distribution of ML30 reactive constituents was very low on the cell surface. Reactivities of each of the monoclonal antibodies were tested on frozen sections of cartilage. Significant reactivity was found only with ML30, and the staining was only associated with chondrocytes, not with the cartilage matrix surrounding the cells. These findings may have significance in view of the possibility that an hsp homologue may be a target for inciting or perpetuating the autoimmune process in rheumatoid arthritis.

Antibodies, Monoclonal↗
PubMedDate not supplied

Pyogenic granuloma gravidarum of the nasal fossa: CT features.

We present a case of a pregnant patient with a rapidly growing mass within the nasal fossa that was imaged by CT 2 weeks postpartum. Concern for malignancy existed and biopsy was performed, revealing pyogenic granuloma gravidarum. This uncommon lesion should be considered in any gravid patient when a mass occurs within the mouth or nasal fossa.

Adult↗