Yohimbine-induced bronchospasm.
Yohimbine is an alpha-2 blocking agent which also increases cholinergic activity. This medication is used to treat male impotence. We report a case of yohimbine-induced bronchospasm.
Biomedical subjects
Publications and source records attributed to E Landis.
Yohimbine is an alpha-2 blocking agent which also increases cholinergic activity. This medication is used to treat male impotence. We report a case of yohimbine-induced bronchospasm.
We studied bacterial adherence to uroepithelial cells of female patients in relation to the menstrual cycle. We determined the number of bacteria demonstrable on native cells and the number of adhering bacteria after incubation with E. coli. Free bacteria and uroepithelial cells with adhering bacteria were optimally separated by differential centrifugation using sodium metrizoate (9.6%) and dextran (5.6%) (Lymphoprep). Thus, contamination of the cell preparation by free (non-adhering) bacteria was avoided and results were well reproducible. A median of five bacteria/cell (range 0-19) was observed for uroepithelial cells obtained from urine of female patients. Such bacteria were mostly rods. After in vitro incubation with E. coli cultures, a median of 33 bacteria/cell (range 17-54) was counted. Our improved methodology failed to demonstrate a relationship between bacterial adhesion and the menstrual cycle.
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PURPOSE: This study was developed to test the hypothesis that intensive biofeedback and relaxation training may favorably affect chronic tinnitus. PATIENTS AND METHODS: Seven subjects with chronic tinnitus of moderate to severe intensity engaged in an intensive 5-month program of weekly, individual 90 minute sessions. All individuals attained a high standard of proficiency following training by a biofeedback specialist. A biofeedback unit was provided each subject for daily practice. Audiometric matching of tinnitus pitch and loudness and subjective comparisons of tinnitus loudness were conducted before and after every session. RESULT: Audiometric evaluation showed no changes in tinnitus loudness. Nevertheless, all subjects gained satisfaction from the training. Three reported substantial psychological benefits in coping with tinnitus, two described moderate improvement, and two experienced modest gains. CONCLUSIONS: These results highlight the role of psychological factors in tinnitus management and indicate that biofeedback-relaxation training may be useful therapy for coping with stresses of tinnitus.
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