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Biomedical subjects

E Laurens

Publications and source records attributed to E Laurens.

7 recordsLinked to original sources

[Evaluation of a prevention program against nosocomial rotavirus infections in a pediatric ward].

UNLABELLED: The incidence of nosocomial rotavirus infections was evaluated by a study made in the pediatric ward in Cholet during the winter of 1993-1994. A second study was performed three years later at the same place and in similar conditions in order to evaluate the efficacy of the prevention measures taken in between. PATIENTS AND METHODS: All children below three years of age and admitted to hospital between 1 December 1996 and 15 March 1997 were included in the prospective study (348 children). Fecal specimens were collected for each patient at admission in order to search for rotavirus. Then, a second stool analysis was performed if diarrhea occurred during hospitalization or within 48 hours of discharge. These last cases were detected by a phone call. RESULTS: Thirty percent of the children had diarrhea at admission to hospital (19.3% in 1993-1994). Rotavirus was present in 11.8% of the first stool analyses (8.6% in 1993-1994). The rotavirus nosocomial infection rate has decreased from 3.7% (13 cases) in 1993-1994 to 2.9% (ten cases). The mean length of hospitalization has also decreased from 2.7 to 1.6 days. CONCLUSION: The decrease in the rotavirus nosocomial infection rate leads to enforcing the prevention measures, among which the most important seems to us to be the short length of stay. However, the study also shows the limits of prevention that are linked to the virus characteristics and the conditions of hospitalization.

Child, Preschool↗

[Cryptococcus neoformans arthritis. A case report].

Cryptococcus neoformans infection generally is rare, particularly in the hand. It is for this reason that we present the case of a 50-year-old patient with C. neoformans infection over his IPP articulation.

Arthritis, Infectious↗

[Nosocomial Aeromonas hydrophila pneumonia complicating toxic coma].

A 24-year-old male homosexual drug addict was admitted in coma and circulatory failure after a 10 g overdose of acebutolol. The usual resuscitative measures were undertaken, together with administration of adrenaline and gastric lavage. Six hours of external cardiac massage and pacing, and high catecholamine doses (36 mg.h-1 of adrenaline and 60 micrograms.kg-1 x min-1 of dobutamine) were required before the circulatory system became again spontaneously efficient. After this acute episode, the patient improved despite acute tubular necrosis. On the third day, bilateral alveolar and interstitial lesions were found on the chest film. Bronchoalveolar lavage and protected distal brushings were carried out. Both Aeromonas hydrophila and Staphylococcus aureus were found in the cultured brushings. Treatment with ceftriaxone, vancomycin and amikacin was introduced. This nosocomial pneumonia was very haemorrhagic, resulting in several bloody casts responsible for several episodes of atelectasis. The patient was definitely extubated on the 18th day, and left the ICU 23 days later without any sequela. His HIV status was negative. Four other infections with the same strain of Aeromonas hydrophila occurred at the same time as this patient's. The common source for this germ was found to be soft water. Several measures have since been undertaken: removal of a centralized water softener, filtration and higher chlorine content in the water circuit, and updating of intensive care protocols for disinfection of equipment.

Acebutolol↗

[Primary Salmonella brandenburg peritonitis in a non-immunosuppressed female patient].

Primary peritonitis is rare; the bacteria involved are mainly, by order of frequency: Escherichia coli, Streptococcus pneumoniae, and the other streptococci. Extraintestinal sites of minor salmonellosis are exceptional, although they are constantly progressing, especially since the spread of the HIV-induced epidemic. We report one case of primary Salmonella brandenburg peritonitis, whose mechanism could not be explained, in a non-immunodepressive female patient.

Female↗