Biomedical subjects

E Leonard

Publications and source records attributed to E Leonard.

9 recordsLinked to original sources

PubMed1989

A computerized kinematic diagnostic system.

This paper describes the instrumentation developed for a clinical system that measures upper extremity kinematics in normal and cerebral palsied children. The ability to diagnose cerebral palsy during early and midinfancy is influenced by the fact that movement and postural abnormalities become apparent only over time, and are not readily detectable until there is sufficient abnormality so that it can be viewed by gross inspection during clinical examination. The methodology presented here serves to discriminate normal from deviant movement at an earlier age than what is presently possible, and may also result in alternative therapeutic intervention.

Biomechanical Phenomena↗

PubMed1987

Lymphocytes and lymphokines in aplastic anemia: pathogenic role and implications for pathogenesis.

Clinical observations first suggested an immune basis for aplastic anemia. Laboratory studies have implicated a suppressor T lymphocyte producing molecules like gamma-interferon that inhibit hematopoiesis. Extrapolation from in vitro studies is complicated by synergy and antagonism among lymphokines and interleukins, the presence of regulators of proliferation produced by bone marrow cells, and possible differences between endogenous and exogenously administered molecules on cell growth.

Anemia, Aplastic↗

PubMed1985

Teaching car passenger safety to preschool children.

An educational curriculum entitled "Bucklebear" was designed to increase safety seat and seat belt use in young children enrolled in preschool programs (day care centers and nursery schools). Three basic concepts were emphasized: (1) "buckling up" is a good habit for everyone for every ride; (2) the back seat is the best seat; and (3) there are desirable passenger behaviors. The curriculum included training workshops with teachers, parent meetings, classroom lessons, sound filmstrip, puppet play, and many other activities. Six experimental programs and seven control programs with 402 and 427 enrolled children, respectively, participated. After their participation in the educational curriculum, children in the experimental program increased their use of a safety seat or seat belt from 21.9% to 44.3%. These children also increased their knowledge and simulated practice of car passenger safety.

Accident Prevention↗

PubMed1979