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Biomedical subjects

E Leroy-Terquem

Publications and source records attributed to E Leroy-Terquem.

9 recordsLinked to original sources
PubMed2005

[Lung cancer and peritoneal mesothelioma: two complications of asbestos exposure in the same patient].

INTRODUCTION: Association of a lung cancer and a malignant peritoneal mesothelioma is reported in a 78-year-old patient with significant asbestos exposure. OBSERVATION: After exploration of an intra-pulmonary opacity, with inspissated pleura, the diagnosis of primary pulmonary adenocarcinoma was obtained by thoracotomy in April 1999. In February 2002, the diagnosis of peritoneal mesothelioma was made by laparoscopy. The course was marked by irreducible ascites and was fatal 7 months after the diagnosis of peritoneal mesothelioma. CONCLUSION: Malignant mesothelioma is a rare disease and even rare in association with lung cancer.

Aged↗
PubMed2005

[Exclusive surgical treatment of Mycobacterium xenopi infection of a pulmonary cavity].

The diagnosis of pulmonary infection due to Mycobacterium xenopi was retained in a 48-year-old immunocompetent patient. The lesion was isolated in a peripheral region and was well limited. Exclusive surgical treatment was undertaken. Cure was complete without recurrence at three years. This case illustrates that in certain cases environmental mycobacteriosis with a very limited lesion may respond very well to surgical resection, an interesting alternative to medication.

Female↗
PubMed2004

[Hyperplasia of the thymus in Graves' disease. A case report].

Graves' disease is rarely associated with hypertrophy of the thymus which takes on a pseudotumor aspect. We observed a case in a 40-year-old woman who presented clinical and biological hyperthyroidism with anti-TSH receptor antibodies, favoring the diagnosis of Graves' disease which was confirmed by scintigraphy. The chest x-ray performed because of chest pain revealed enlargement of the mediastinum. The thoracic CT-scan without contrast injected showed a pseudotumor aspect of the thymus. Medical treatment with anti-thyroid drugs and beta blockers led to regression of the thymus mass. Knowledge of this type of association can avoid unnecessary thymus surgery. The clinical course is favorable irrespective of the type of anti-thyroid drug given.

Adult↗
PubMed2003

[Thymoma and autoimmune thyroiditis. A case report].

We report an association between a thymus tumor and autoimmune thyroiditis. This association is probably related to loss of immune control secondary to loss of thymus integrity. A 48-year-old woman was hospitalized for thoracic pain. Her past history included thyroiditis treated by L-thyroxin for two years. The chest x-ray demonstrated a mediastinal opacity which was confirmed by computed tomography. Surgical resection was performed and histological analysis of the surgical specimen confirmed the diagnosis of lympho-epithelial thymoma. Thyroid immunity tests demonstrated the presence of anti-peroxidase antibodies confirming the diagnosis of Hashimoto's thyroiditis. Chest x-ray and CT-scan are indicated in patients with autoimmune thyroiditis to search for a thymic mass. Conversely, search for autoimmune thyroiditis is warranted in patients with an identified thymic mass.

Female↗
PubMed2001

[Rare association of hypoparathyroidism and mediastinal-pulmonary sarcoidosis].

We report the case of a 52-year-old woman who presented hypoparathyroidism and sarcoidosis. The hypoparathyroidism developed 8 years after the diagnosis of sarcoidosis. No element in favor of an autoimmune disease of the parathyroid could be evidenced. Pathology and immunology blood tests were equally noncontributive. Another pathophysiological mechanism, possibly sarcoidic granulomatous infiltration of the parathyroid glands, was suspected. The patient also presented apparently coincidental vitiligo.

Biopsy↗
PubMed2000

[Right heart failure caused by thiamine deficiency (cardiac beriberi)].

BACKGROUND: Vitamin B1 deficiency (beriberi) is very uncommon in France. It leads to high output cardiac failure totally different from the situation observed in alcoholic patients. We report a typical case of cardiac beriberi. CASE REPORT: The patient was referred for dyspnea with high output cardiac failure. Echocardiography evidenced severe pulmonary hypertension and high cardiac output. The more common causes of heart failure were ruled out. The dietary habits of the patient (suggested beriberi which was confirmed by the low serum thiamin and therapeutic test with vitamin B1. DISCUSSION: High output cardiac failure should suggest possible Shoshin beriberi, particularly in subjects with imported dietary habits living in a precarious socioeconomic situation.

Beriberi↗
PubMed1989

[Aspergillosis and radiation-induced pneumonia. What relationship? Apropos of 2 cases].

The authors report the cases of 2 patients who underwent lobectomy followed by irradiation for lung cancer and subsequently developed an aspergillus-infected cavity in the irradiated lung parenchyma. It is far from certain that aspergillosis must always develop in a pre-existing cavity. In cases where it developed on post-radiotherapy lung lesions, our 2 patients and a review of the literature encline us to believe that the fungus itself is responsible for the formation of cavities in lesions of radiation pneumonia. Treatment of such disease can only be surgical, and in spite of post-irradiation and post-surgery sclerosis, elective excision of the lesions is the best solution.

Adult↗
PubMed1987

[Mycobacterium xenopi infection in emphysematous bulla. Apropos of 4 cases operated on].

The authors presented their observations of four patients who were operated on for a supra-infection of emphysematous bullae by Mycobacterium xenopi. In two cases the patients were operated on without a diagnosis and excision of the right upper lobe assured their cure. The other patient underwent a decortication and ultimately relapsed. The fourth had a bilateral apical infection and underwent bilateral excision. A survey of the literature leads one to think that pulmonary infections with a Mycobacterium xenopi occur in emphysematous bullae more often than is generally thought. The unreliability of the results of antituberculous drugs, the complications of treatment and the risks of recurrence after treatment are well known. Controlled surgical excision of the lesions, which is most often followed by a definitive cure, always merits consideration as part of the therapeutic arsenal.

Adult↗