PubMed1979
Reported in this paper is experience so far obtained from graduated or stepwise treatment of carcinoma in situ. The report is based on the author's own experience obtained from 716 cases as well as on another 342 carcinomas in situ which had been evaluated earlier and elsewhere by Mosler and co-workers. The five-year healing rate accounted for 99.87 per cent. The first and second periods of follow-up checks were compared for all 1,058 in situ carcinoma cases under review, and the following conclusion were drawn: 1. More women were involved in prophylactic gynaecological checks. - 2. The age peak of carcinoma in situ cases in the second follow-up period was two years below that observed in the first period. - 3. Decline in cases with carcinoma location in ectocervix only, but increase in cases with carcinomas in situ of endocervical or endocervical together with ectocervical locations. - The following advantages are likely to be obtainable from conisation over general use of simple hysterectomy and even more over radical surgery, provided observance of the conditions specified in this paper: 1 Mitigation of physical and psychic surgical trauma and its consequences; - 2. Less exposure to severe potential intra-operative and/or postoperative complications; - 3. Savings on cost of treatment resulting from shorter hospitalisation and reduced need for nursing, medicaments, and attention, using hardware.