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Biomedical subjects

E Lyon

Publications and source records attributed to E Lyon.

33 records · Page 2Linked to original sources
PubMed1989

MEDLINE-for-Medics: an outline searching course for health-care professionals.

An online searching course for health professionals was initiated at a university medical school. A group of end users were taught to search the MEDLINE database on DATA-STAR and their subsequent online progress was monitored. The preliminary survey by questionnaire, pretraining interviews, the tutorial programme, course evaluation and end-user feedback were described. Logsheets showed that most end-user searches were for research purposes, although some were for patient care. The effects of CD-ROM on online end-user searching were discussed and it was suggested that direct online access to information might be a more appropriate medium for busy clinical and academic staff.

Academic Medical Centers↗
PubMed1985

Endoscopic ureteropyelostomy: opening the obliterated ureteropelvic junction with nephroscopy and flexible ureteropyeloscopy.

Endoscopic re-establishment of a totally obstructed ureteropelvic junction was accomplished in 2 patients. The combined use of rigid percutaneous nephroscopy and flexible ureteropyeloscopy provided full visualization of the obliterated segment, and allowed accurate electroincision into the ureter and placement of a wire and catheter into the lumen. This technique demonstrates the potential therapeutic applications of flexible ureteropyeloscopy and should be considered for the initial treatment of the obliterated ureteropelvic junction.

Aged↗
PubMed1981

Biologic properties of iscador: a Viscum album preparation I. Hyperplasia of the thymic cortex and accelerated regeneration of hematopoietic cells following X-irradiation.

We demonstrated that a preparation of Viscum album (Iscador) has unusual effects on the immune system. In CD-1 mice, the mean weight of the thymus increased from 45 to 85 mg. following six daily intraperitoneal injections of 2.5 mg. of Iscador. The thymic trophic influence was maintained over a long period of time. Sprague-Dawley rats treated with Iscador for 16 weeks showed an increase of 78% in thymic weight over controls. The increased weight of the thymus was due to increased proliferation of cortical thymocytes. The number of blast cells in the outer cortex of the thymus increased within 2 days of the first injection and remained at high levels. Thymocytes of Iscador-treated animals were 29 times more responsive to Concanavalin A than those of untreated controls. Iscador increased the amount of antibody produced by animals injected with sheep red blood cells if it was injected after the antigen. Iscador also had effects on hematopoietic cells. It accelerated the recovery of hematopoietic tissue in bone marrow and spleens of irradiated animals. We believe that V. album preparations may be valuable reagents for perturbing thymus function.

Animals↗