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Biomedical subjects

E M Dovgopol

Publications and source records attributed to E M Dovgopol.

3 recordsLinked to original sources

Non-dipole components of the heart electrical field in electrocardiographic diagnosis of combined ventricular hypertrophy.

A new method of ECG diagnosis, based on a mathematical model of electrical heart generator as a mobile dipole, was clinically verified in 10 healthy subjects and 2 patients with combined cardiopathy and pronounced bilateral ventricular hypertrophy. Electrocardiograms were recorded in 80 unipolar leads from the body surface; recordings were processed by a computer. The output information were the pathways of the heart electrical centre (dipole) during the heart cycle. The trajectories in patients with combined ventricular hypertrophy markedly differed--even in the absence of ECG changes in standard leads--from trajectories in healthy subjects. The new method of ECG diagnosis consequently offers information which cannot be obtained when using conventional and corrected orthogonal ECG leads.

Adult↗

Mobile equivalent heart generator (migrating dipole).

The study is concerned with quantitative mapping of electrocardiographic potentials on the human body surface at various applications of equivalent multipole heart generators. The accuracy or reproduction of the electrical heart field with the application of mobile and immobile dipole and quadrupole generators is compared. The immobile equivalent generator (EG) is fixed in the geometrical centre of the trunk, whereas the mobile EG follows the path of the electrical heart centre during the heart cycle. Four healthy subjects and two patients with permanent postmyocardial ECG changes were examined. On transition from the immobile to the mobile model, in both groups of probands the relative contribution of the quadrupole component to the total potential of the body surface steeply diminished, with consequent substantial increase in accuracy of the dipole heart description. The dipole following the path of the electric heart centre during the heart cycle represents one of the most promising models, and deserves attentive clinical testing.

Electrocardiography↗

[Study of a mobile multipolar equivalent generator of the human heart].

Multipolar expansion convergence can be improved by changing the structure of the model. The generator is not fixed in a certain point but is supposed to move along the electric heart centre trajectory during the cardiac cycle. Six normal subjects and three patients who had severe myocardial infarction with specific changes in ECG were studied. In all the cases, the dipole and quadrupole contributions to the averaged ECG potential of the thoracic surface were determined. With replacement of an immovable model by a movable one, the mean square quadrupole contribution was found to decrease drastically, i. e. considerable improvement of the multipole expansion convergence has been observed. Therefore, the model of the equivalent generator moving along the heart electric centre trajectory appears to be one of the most promising models and is to be specially studied in the clinic.

Biophysical Phenomena↗