International aid and medical practice in the less-developed world: doing it right.
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Biomedical subjects
Publications and source records attributed to E M Einterz.
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BACKGROUND: Though little known by medical personnel, an immediate nonallergic psychotic reaction to intramuscular procaine penicillin has been reported occasionally from many countries since 1951. MATERIALS AND METHODS: A case report describes a patient whose violent behavior, provoked by this reaction, resulted in legal action taken against him. Two other nonviolent cases are presented and are followed by a review of the literature. RESULTS: Signs and symptoms of this reaction that appears to be to the procaine component resemble a pressor response and are therefore contrary to the signs and symptoms of an anaphylactic reaction. Anxiety, hallucinations, hypertension, and tachycardia are characteristic. The reaction is self-limited. Long-term psychologic sequelae might be averted by adequate reassurance. CONCLUSIONS: The importance of procaine penicillin as an essential drug in many parts of the world should not be diminished; however, recognition of acute nonallergic psychotic reactions is of paramount importance to assure proper patient management and to avoid misinterpretation of aggressive behavior.
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Sometimes efforts to improve the quality of life can hasten the destruction of a whole way of life, in which case the "beneficiaries" can lose much more than they gain. This presents health workers and planners with difficult choices.
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Two-hundred-and-thirty-seven consecutive cases of neonatal tetanus treated in a rural health facility in Nigeria were reviewed. In spite of a high proportion of short incubation cases, a relatively simple, low-cost protocol yielded results compatible with those obtained in tertiary care settings in Africa. An incubation period of 6 days or less was the strongest predictor of mortality. Other prognostic factors were related to cord care and affected boys more than girls. Incidence was 40 per cent greater during the rainy season than during the dry season.
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The epidemiology of common diseases of infants seen in district health service clinics in a culturally heterogeneous population in northern Cameroon was studied. Significantly higher incidences were found for respiratory tract infection in infants of non-Moslem households, and for diarrhoea in infants of Moslem households. A subsequent interview survey of parents of children aged 0-5 years revealed a higher prevalence of smokers and millet stalk kitchens in the compounds of non-Moslems. Other possible risk factors were explored. The findings indicated that in this area the influence of culture on disease in infants is strong, and epidemiological differences among cultural groups should be considered in the design of disease control programmes in the community.
Following the identification of differences in disease patterns among infants from households of different social groups (Moslem and non-Moslem) in northern Cameroon, 534 mothers and their children 0-23 months old were studied to determine early childhood feeding practices in the 2 groups. Several significant differences were revealed. Compared with non-Moslem infants, Moslems were more likely to be given animal milk instead of breast milk before the age of 3 d. On average, millet pap was introduced to Moslem babies between their 1st and 2nd months and to non-Moslem babies between their 3rd and 4th months. Moslem mothers more commonly prepared pap with oil or cow butter as an ingredient. Moslem mothers also planned to wean their children at an earlier age than non-Moslems and were less likely to report boiling their children's drinking water. Moslem mothers of infants less than 5 months old were likely to believe their breast milk was insufficient. The implications of these findings on the higher incidence of infant diarrhoea, stunting and early childhood death among Moslems are discussed.