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Biomedical subjects

E M Elamin

Publications and source records attributed to E M Elamin.

7 recordsLinked to original sources
PubMed2005

Uncommon clinical presentations of cutaneous leishmaniasis in Sudan.

Cutaneous leishmaniasis in Sudan is caused by Leishmania major zymodeme LON1. Self-healing usually occurs within 1 year but occasionally its duration is prolonged and treatment is required. The clinical forms are ulcers, nodules and noduloulcerative lesions. Here we describe seven patients with uncommon lesions that were difficult to recognize as Leishmania infections. These included mycetoma-like lesions, lesions that resembled L. tropica infection and others. One HIV/AIDS patient had Kaposi's sarcoma with Leishmania parasites in the Kaposi lesions. Most of these uncommon clinical forms were difficult to treat. The diagnosis depended on a high degree of suspicion and the demonstration of parasites in smears or culture. PCR was used to characterize parasites from the patients described here. Leishmania major was found by kDNA PCR in all patients, except one, who had a leishmanioma due to L. donovani. In three patients, including one with a L. tropica like-lesion, the parasites were confirmed as L. major by gp63 PCR-RFLP.

Adult↗
PubMed2002

Is daily mvi required in patients receiving parenteral nutrition?

Between November 1996 and January 1999 there was a nationwide shortage of intravenous multivitamins (MVI) in the US. We investigated whether patients who received parenteral nutrition (PN) with MVI three times per week instead of daily developed clinical manifestations of vitamin deficiency during that period. Five patients were enrolled in the study All received home PN as their sole source of nutrition for at least six months. None of these patients showed clinical manifestations of vitamin deficiency. In addition, compared to daily MVI administration, supplementation with MVI three times per week saved $1,000 per patient per year. This preliminary study raises the question of how much MVI is needed to prevent vitamin deficiency. Using MVI three days a week instead of daily would substantially reduce the cost of treatment and might reduce the risk of infections for these patients.

Adult↗
PubMed2001

Recent advances in pulmonary embolism diagnosis and management.

Pulmonary embolism remains a major problem in clinical practice. Pulmonary angiography remains the most accurate diagnostic procedure. Standard therapy includes heparin then warfarin, and now low molecular weight heparin. The role of prophylactic measures cannot be over emphasized.

Decision Trees↗
PubMed1996

Calcifying panniculitis with renal failure: a new management approach.

A 60-year-old woman with chronic renal failure, hyperphosphatemia, normocalcemia and hyperparathyroidism presented with skin and subcutaneous tissue necrosis over the upper lateral aspects of both thighs which became progressively worse with subsequent ulceration over the period of 1 week. A biopsy of the affected skin and subcutaneous tissues demonstrated discrete foci of calcification compatible with the diagnosis of calcifying panniculitis. While it was possible to control the patient's hyperphosphatemia using magnesium carbonate, local ulcer care, including daily whirlpool and repeated local surgical excision, failed to stop the progression of the surrounding skin and subcutaneous tissue necrosis with subsequent ulceration. A trial of oral prednisone for a total of 10 days followed by oral cimetidine for 3 months resulted in complete healing at the incision sites without recurrence after 9 months. In this case of calcifying panniculitis the conditions for calciphylaxis were present, and a new management approach was applied.

Anti-Inflammatory Agents↗
PubMedDate not supplied

Lipoblastoma in a four-year-old African child.

A four-year old Sudanese child presented with a growing mass in the medial aspect of the right thigh. The mass appeared during the neonatal period. On clinical examination a diagnosis of lipoblastoma was entertained on the basis of the patient's age and the clinical features of the mass. The tumor was completely excised surgically. The clinical diagnosis of lipoblastoma was confirmed pathologically. Follow-up of the patient for 6 months postoperatively showed no evidence of recurrence.

Child, Preschool↗
PubMedDate not supplied

Isolated hypogonadotropic hypogonadism in a man with a history of head trauma during childhood.

OBJECTIVE: To report a case of isolated hypogonadotropic hypogonadism as a delayed consequence of major head injury. METHODS: We present the relevant history, findings on physical examination, and results of laboratory evaluation, and supportive data from appropriate reports in the literature are reviewed. RESULTS: A 37-year-old man with progressive loss of libido, impotence, and gradual loss of facial and axillary hair had sustained severe trauma to the head (sufficient to cause blindness in one eye) in a fall from a tree at 7 years of age. Physical examination and laboratory investigations substantiated the presence of isolated hypogonadotropic hypogonadism. Other causes of hypogonadotropic hypogonadism, including Kallmann's syndrome, were excluded. CONCLUSION: Severe head injury should be considered in the differential diagnosis of isolated hypogonadotropic hypogonadism. Long-term follow-up and endocrine assessment may be important in patients who have sustained severe head injury.

Journal Article↗