Biomedical subjects

E M Friedler

Publications and source records attributed to E M Friedler.

3 recordsLinked to original sources

PubMed1985

Fluoride prescribing patterns among primary care physicians.

Fluoride supplement prescribing habits of US Air Force primary care physicians were studied. A questionnaire was sent to all active duty Air Force obstetricians, family physicians, and pediatricians assigned within the continental United States. Few obstetricians and family physicians in the Air Force currently prescribe prenatal fluoride supplements. The majority of respondents are skeptical of its efficacy or state that local water contains adequate amounts. Only 2.5 percent of all physicians question prenatal fluoride's safety. Fluoride supplements for breast-feeding infants are correctly prescribed by 80 percent of pediatricians and 54 percent of family physicians (P = .0002). Pediatricians more often know the local concentration of fluoridated water and more readily prescribe fluoride for children of all ages. Primary care physicians, especially family physicians, are in an excellent position to practice caries prevention. The survey results indicate a need for more physician education on the current issues and proper use of fluoride supplements.

Adolescent↗

PubMed1981

Eosinophilic fasciitis: an underdiagnosed syndrome.

Eosinophilic fasciitis is characterized by peripheral eosinophilia, diffuse induration of the skin (particularly of the extremities), thickened fascia, and responsiveness to corticosteroids. Since it was first described in 1974, 36 cases have been reported. We have presented three new cases diagnosed in our community hospital during the last 27 months, with reports on their follow-up while being treated with corticosteroids. We believe the disorder to be more common than reports indicate.

Adult↗

PubMed1975

Serum lymphocytotoxins in inflammatory bowel disease. Studies of frequency and specificity for lymphocyte subpopulations.

Serum cold-reactive lymphocytotoxin (LCT) was detected in twenty-two of fifty-six (40%) patients with inflammatory bowel disease (IBD). The frequency of LCT detection was similar in Crohn's disease and ulcerative colitis. Cytotoxicity testing against T or B cell-enriched peripheral blood lymphocytes from normal donors, together with absorption experiments, indicated that LCT in IBD was reactive against determinants on both cell subpopulations. Reactivity against T cells from patients with common variable immunodeficiency was significantly less than with normal donor T cells. LCT in IBD could not be related to prior allogeneic sensitization and its presence appeared to be unrelated to disease activity or drug therapy. No correlation was found between LCT and peripheral blood T- or B-cell numbers. The present findings suggest the need for further investigation of the role of infectious agents in the pathogenesis of IBD.

Absorption↗