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Biomedical subjects

E M Gross

Publications and source records attributed to E M Gross.

At least 19 recordsLinked to original sources
PubMed2001

Light-emitting electrochemical processes.

Electrochemical processes leading to light emission are reviewed, with emphasis on aspects of this subject relevant to the understanding and optimization of electrogenerated luminescence (EL) in organic thin-film materials. The basic energetic requirements of light emission from electrochemically initiated solution redox reactions [electrogenerated chemiluminescence (ECL)] are reviewed first. This review is followed by a discussion of light-emitting electrochemical processes that have been observed in hybrids of ionically conducting polymers and electronically conducting polymers. Finally, the features of EL in insulating polymers and molecular thin films are reviewed, along with recent electrochemical and ECL studies of the small-molecule components of certain organic light-emitting diodes. These studies provide a conceptual framework for understanding and optimizing these materials and the EL process.

Journal Article↗
PubMed2000

Intractable benign paroxysmal positional vertigo in patients with Meniere's disease.

OBJECTIVE: To provide a detailed description of the coexistence of benign paroxysmal positional vertigo (BPPV) and Meniere's disease in individuals and to offer a possible mechanism that explains the findings in these patients. STUDY DESIGN: Retrospective. METHODS: Chart review. RESULTS: Of 162 patients diagnosed with Meniere's disease between January 1998 and January 1999, 9 were found to have both "definite" Meniere's disease and "certain" BPPV. Meniere's symptoms preceded the onset of BPPV in all of our patients. Seven of the 9 patients were female. Except for one patient who experienced BPPV bilaterally, BPPV was limited to the same ear as the Meniere's disease. All patients presented with intractable BPPV that did not respond completely to otolith repositioning procedures. A detailed description of five patients is presented. CONCLUSION: Our data, in conjunction with that of others, suggest that Meniere's disease may predispose patients to intractable BPPV. Hydropically induced damage to the maculae of the utricle and saccule or partial obstruction of the membranous labyrinth may be possible mechanisms that explain the coexistence of Meniere's disease and BPPV.

Acoustic Maculae↗
PubMed2000

Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report.

Azithromycin, an azalide antibiotic, rarely causes ototoxicity. According to the few reports in existence, azithromycin-induced ototoxicity occurred following prolonged high-dose therapy in patients with acquired immunodeficiency syndrome and resulted in a reversible sensorineural hearing loss. We present a case of irreversible sensorineural hearing loss due to azithromycin ototoxicity in an otherwise healthy woman following low-dose exposure to azithromycin.

Adult↗
PubMed1991

The epidemiology of echinococcosis in Israel.

Shifts in population and employment patterns in Israel since 1948 have been accompanied by profound changes in the distribution of echinococcal disease. Formerly, it was most commonly imported with the mass immigration of Jews after 1948 from the Arab countries of North Africa and Asia Minor, and appeared to be relatively uncommon in Israel-born Jews and Arabs. In 1980 the disease was made notifiable, and this paper presents a review of the years 1981-1989. The prevalence pattern that prevailed after the end of mass immigration has reversed so that cases are now twice as common in Arabs as in Jews. Among the Arabs the disease appears most commonly in the north of the country, especially among the Druze, less commonly among Christians and least in Muslims. We suggest that this prevalence pattern is related largely to home slaughter of sheep, to differing attitudes to dogs, and possibly also to the hunting of wild pig. Targetted education and better enforcement of existing regulations can lead to a reduction in disease.

Adolescent↗
PubMed1988

Increased risk of suicide in persons with AIDS.

The rate of suicide has been reported to be higher in persons with chronic and life-threatening illnesses (eg, cancer, Huntington's disease, and renal failure). We studied the rate of suicide in 1985 in New York City residents diagnosed with the acquired immunodeficiency syndrome (AIDS). There were 668 suicides in New York City residents in 1985, yielding a rate of 9.29 per 100,000 person-years. In men aged 20 to 59 years without a known diagnosis of AIDS, the rate was 18.75 per 100,000 person-years. There were 3828 individuals who lived with the diagnosis of AIDS for some part, or all, of 1985. There were 12 suicides in men aged 20 to 59 years from this group who lived 1763.25 person-years with a diagnosis of AIDS. This yields a suicide rate of 680.56 per 100,000 person-years. Thus, the relative risk of suicide in men with AIDS aged 20 to 59 years was 36.30 times (95% confidence limits, 20.45 to 64.42) that of men aged 20 to 59 years without this diagnosis, and 66.15 times (95% confidence limits, 37.38 to 117.06) that of the general population. We conclude that AIDS represents a significant risk factor for suicide.

Acquired Immunodeficiency Syndrome↗
PubMed1987

Comparison of two dosage schedules of doxycycline in children with rickettsial spotted fever.

We carried out a randomized clinical trial with oral doxycycline in children with Israel rickettsial spotted fever. Our purpose was to investigate whether an abbreviated course of therapy with this drug (until the patient was afebrile plus one day) would be as effective as a one-week regimen of therapy. Results with 50 pediatric patients during this three-year study indicated that the abbreviated treatment regimen was as effective. This clinical trial may serve as a model for determining shorter durations of therapy for other diseases.

Child↗
PubMed1987

Israeli rickettsial spotted fever in children. A review of 54 cases.

We observed and recorded clinical and laboratory data from 54 children with fever and a maculo-papular rash admitted to Soroka Medical Center, Beersheva, Israel suffering from serologically confirmed rickettsial spotted fever. The rash generally began on the palms and soles and extended centripetally to the torso. Other clinical findings included myalgia, headache, hepatomegaly, and splenomegaly. None had a "tache noire". A left shift in the white cells, leucopenia, thrombocytopenia, hyponatraemia and impaired liver function tests were common laboratory abnormalities. All recovered following oral doxycycline therapy. Serious sequelae such as myocarditis, encephalitis, and disseminated intravascular coagulation, as reported in Rocky Mountain spotted fever, did not occur.

Adolescent↗
PubMed1986

A study of homicides in Manhattan, 1981.

There were 573 persons murdered in Manhattan (New York) during 1981 for an overall rate of 40.5 per 100,000 population. The male, young, and Black or Latino populations were at higher risk of being homicide victims. For male victims, the homicides were the result of disputes in 37.6 per cent of the cases, drug-related activities in 37.6 per cent, and robbery and other criminal activities in 24.8 per cent of cases. For female victims, homicides resulted from disputes in 62.2 per cent of cases, drug-related activities in 13.8 per cent, and robberies in 20.0 per cent of cases. The observed proportion of homicides related to drug and other criminal activities was higher than has been reported previously in the United States. The role of alcohol continued to be important in homicides related to disputes. The authors stress the importance of differentiating drug-related homicides from those associated with other criminal activities.

Adolescent↗
PubMed1985

Post-exposure rabies prophylaxis: establishing effectiveness of abbreviated treatments.

Several publications have reported recently the apparently successful use of human diploid cell rabies vaccine (HDCV) in volumes of less than the 6 X 1.0 cm3 dosage schedule currently recommended by the World Health Organization for post-exposure rabies prophylaxis. The newer proposed treatments are advocated to economize on an expensive product that may be available rarely in many Third World areas.

Animals↗
PubMed1984

Toxocara canis infection in dogs in Beersheba, Israel.

In the desert city of Beersheba, Israel, a survey was made of the infection rate of Toxocara canis in dogs. 3.0% of dogs destroyed at the municipal dog pound had intestinal T. canis. 7% of faecal samples gathered from day care centres throughout the city were shown to contain T. canis eggs. This low rate of infection could possibly be explained by the hot, arid climatic conditions which may render eggs non-infective or by the sandy soil in the area that may cover faeces containing T. canis ova and make the eggs unavailable to other dogs.

Animals↗