[Adequacy of applied mathematical methods in the detection of biorhythms].
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Biomedical subjects
Publications and source records attributed to E M Krishchian.
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Seventy normal persons and 100 patients with coronary disease were examined for circadian rhythms of urine and minerals excretion. The data obtained demonstrate that normal persons were characterized by circadian rhythms of urine and minerals excretion with a definite confidence interval of mesor and amplitude fluctuations. Angina pectoris of effort was marked by infradian rhythms of mineral excreting renal function. Monotherapy with beta-blockers or calcium antagonists given in courses entailed the recovery of the circadian rhythms of mineral-excreting renal function. Parameters of the rhythms of urine and minerals excretion in patients with angina pectoris of effort and rest noticeably differed from those in patients with angina pectoris of effort. In 30.7 percent of the persons, the use of the mathematic methods did not reveal any significant rhythms. The circadian range was found to predominate among the significant rhythms. Antianginal treatment did not produce any appreciable changes.
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SIgns based on the ordinal properties of the amplitudes of ECG waves, i.e. those using information on their relative values, are of high diagnostic value in the recognition of hypertrophy of the ventricular myocardium. A simple algorithm for the diagnosis of hypertrophy of the ventricular myocardium may be formulated by means of such signs, which will be close in precision to the data issued by a highly experienced specialist.
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The computer-aided (ES computer) system for acquisition, storage and sampling for any set of signs and processing of rhythm-based data is developed. The software is based on the operation system ES computer by using a time share system and a system for database control "Spektr". The informative database contains "The map of chronobiological examinations" and "The meteorologic map".