PubMed Health⌕ Search

Biomedical subjects

E M RENKIN

Publications and source records attributed to E M RENKIN.

16 recordsLinked to original sources
PubMed1961

Permeability of frog skeletal muscle cells to choline.

Using choline-methyl-C(14) as a tracer, it has been shown that choline(+) penetrates into the cells of resting frog skeletal muscle at a rate similar to that of Na(+), and that it escapes from these cells much more slowly than does Na(+). Some implications of these findings are discussed.

Animals↗
PubMed1954

Filtration, diffusion, and molecular sieving through porous cellulose membranes.

1. A study has been made of the diffusion and filtration of a graded series of molecules (including tritium-labelled water, urea, glucose, antipyrine, sucrose, raffinose, and hemoglobin) in aqueous solution through porous cellulose membranes of three degrees of porosity. 2. Experimental results were in close agreement with predictions based on the membrane pore theory of Pappenheimer et al. (1,2). Restriction to molecular diffusion is a function of pore radius and molecular radius described by equation (11) in the text. Molecular sieving during ultrafiltration is a function of total pore area per unit path length, pore radius, molecular radius, and filtration rate given by equations (16) and (19). 3. Estimates of average pore radius made by means of this theory were considerably larger than estimates made by the method of Elford and Ferry (3) (Table II). Sources of error in the latter method are discussed and a new method of membrane calibration is proposed in which the total cross-sectional area of the pores is measured by direct diffusion of isotope-labelled water. 4. Steady-state osmotic pressures of solutions of sucrose and raffinose measured during molecular sieving through cellulose membranes were found to be close to the "ideal" osmotic pressures calculated by van't Hoff's law. Thus the present experimental data support the methods used by Pappenheimer et al. in their studies on living capillary walls as well as their theory of membrane pore permeability.

Cellulose↗