Biomedical subjects
Publications and source records attributed to E M Razack.
Acanthosis palmaris, a recently described dermatologic entity, is often associated with internal malignancy. We report the development, disappearance, and reappearance of this condition in a patient with bullous pemphigoid. Relevant screening tests did not reveal any internal malignant neoplasm. The significance of the appearance and disappearance of the condition is discussed.
Thirty three leprosy patients in reaction were treated with a combination of Metronidazole--Diethyl carbamazine citrate--Chloroquin which was reinforced either with prednisolone and/or Clofazimine in some, depending on the clinical state. The results were quite encouraging as to recommend the combination alone to be the first choice while encountering leprosy patients in reaction early during the maiden spell--at no time in any case was Dapsone withdrawn.
An unusual clinical variant of porokeratosis (Mibelli's disease) appeared in a patient soon after birth; the lesions were widely distributed mostly on the right half of the body. Spontaneous recurrent ulcerations occurred over certain sites. The right foot was grossly deformed as a result of atrophic scarring after ulcerations. Biopsy specimens of the classical lesion showed cornoid lamella. It is suggested that the term "ulcerative systematized porokeratosis" be used to describe this clinical variant of porokeratosis.
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