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Biomedical subjects

E M Schmidt

Publications and source records attributed to E M Schmidt.

At least 37 records · Page 2Linked to original sources
PubMed1977

Intracellular recording from pulsating cerebral cortex.

An instrument has been developed for recording intracellulary from cortical neurons in an exposed pulsating brain. The electrode moves with the brain pulsations maintaining the electrode within the impaled cell. Stable recordings have been obtained for up to 20 min.

Animals↗
PubMed1975

Reexamination of the force relationship of cortical cell discharge patterns with conditioned wrist movements.

Single unit recordings were obtained from 103 precentral cortical cells whose activity was related to an alternate wrist flexion-extension task in monkeys. Although the task was carried out under different loads only a weak relationship between cortical cell firing rates and static force levels was observed for force in one direction. A large change in firing rate occurred, however, when direction of force shifted as a result of a change in the predominant activity between extensor and flexor muscles. The firing patterns of the observed cortical cells suggest that the motor cortex is involved in specifying the muscles to be activated for a given movement and not the level of force to be produced by these muscles. During the dynamic phase of the movement little change in cortical cell firing pattern was observed for large changes in the rate of change of force. Motor cortex cell firing patterns appear to be unrelated to the large values of rate of change of force seen in this experiment.

Animals↗
PubMed1975

An instrument for stable single cell recording from pulsating human cerebral cortex.

An instrument has been developed for positioning microelectrodes near neurons in the exposed pulsating cerebral cortex of man or animals. The electrode moves with the cortex and maintains a fixed relationship with the desired neuron. Stable extracellular single cell recordings have been obtained for 17.5 min from an exposed human brain that pulsated 1.5 mm at the surface.

Cerebral Cortex↗