Left temporal glioma presenting as migraine with typical aura.
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Biomedical subjects
Publications and source records attributed to E Magrotti.
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Twenty-five patients suffering from chronic renal insufficiency and who had been undergoing dialysis for a long time were tested on the Wechsler-Bellevue Intelligence Scale with a control of twenty-five subjects of the same age with a comparable educational and social background. The results of the statistical analysis of the difference between the two groups demonstrates a significant psychological deterioration in the group of uremic patients which was particularly noticeable in the performance test. The rate of deterioration was not significantly related to the duration of the dialysis. At the same time electromyography (motor conduction velocity of the S.P.E. nerve) show in 40% of the uremic patients evidence of neuropathy.
Functional differences between superior and inferior visual hemifields to dot stimuli projected at 5 degrees and 20 degrees from the horizontal meridian, have been studied in 10 subjects. The reaction time method (uncrossed response only) has been employed, by projecting the dot stimuli in each quadrant. The reaction time at 5 degrees is the same in the 4 quadrants, but it increases in each quadrant at 20 degrees stimulation; at 20 degrees a greater speed of the superior hemiretina also results.
Choice reaction time with manual response (right and left hand) to alphabetic stimuli (capital letters A-E = positive stimulus, and R-F = negative stimulus) projected at 5 degrees in the nasal and in temporal hemisfield of the right eye (half of the subjects) and of the left eye (the remaining half) was studied in 12 normal subjects (6 males and 6 females). The RT mean values were the result of the mean of the median of each block of trial, repeated in 4 sessions. The percentage of errors was also considered. The mean RT was calculated for each of the possible 4 experimental conditions hand-hemifield, in the males and females separately, and in all the cases. The data obtained, submitted to the statistical analysis, show a significant superiority of the left hemisphere in the recognition of the alphabetic stimuli, both in males and females, despite the prevalence of the right hand.
Twenty patients suffering from ataxic hemiparesis caused by lacunar infarcts were studied using computerized tomography. Supratentorial lesions were found in nineteen patients (95%) while subtentorial lesion was found in only one patient (5%). In all cases the lesions were localized along the corticopontine pathways, making the hypothesis of injury to this pathway the most valid explanation of ataxia.
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Simple reaction time with manual response (right and left hand) to visual stimuli lateralized was studied in 20 normal subjects at 5, 20 and 35 degree in the nasal and temporal hemifields of the right eye. The reaction time was studied as a function of stimulus eccentricity. Uncrossed and crossed reaction times were examined with particular attention. No prevalence was found, neither of one hand, or of one hemisphere. The global speed of the two hemiretinas was the same, but reaction time increased as a function of stimulus eccentricity; moreover a better performance was obtained stimulating the nasal hemiretina at 35 degrees. Uncrossed reactions, considered on the whole, were faster than crossed ones (7,4 msec); the delay between crossed and uncrossed responses remained constant regardless of the degree of the visual stimuli eccentricity. The AA. concluded that such a difference is mainly dependent upon anatomical structures. The AA. also discuss several and often conflicting literature data and conclude that either the attentional model of the orienting responses as proposed by Kinsbourne, or the stimulus-response conpatibility effects, can be taken into consideration to explain some conflicting results; these results have been obtained by methods in some way different from those performed with present report (choice reaction times, absulute randomisation of the stimuli, response by crossed hands, choice verbal responses).
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