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Biomedical subjects

E Malizia

Publications and source records attributed to E Malizia.

16 recordsLinked to original sources
PubMed1980

Cardiotoxicity from orphenadrine intoxication in humans.

Eight cases of Orphenadrine intoxication were treated in the Resuscitation Centre of Rome's University Medical School. All these cases arrived in coma, after taking an overdose of Orphenadrine in an attempt at suicide. The clinical signs and therapy are reported in detail; the cardiovascular side-effects, in particular those involving arrhythmias are dangerous and life threatening. From the clinical data it is believed that these changes in rhythm are mostly due to the autonomic nervous system (A.N.S.). In fact all the 8 patients survived, without treatment never having been treated with cardiokinetic or antiarrhythmic drugs, but a few were given Diazepam as well as respiratory assistance, cardiovascular assistance, and forced diuresis.

Adolescent↗
PubMed1977

Chlorpromazine plus thiorazidine poisoning and treatment with extracorporeal dialysis.

One case of self-poisoning by 3075 mg of Chlorpromazine and 250 mg Thiorazidine is referred. In this case coma and uremia rose 3 days after the intoxication. Treated with extracorporeal circulation through Travenol Coil kidney, this patient recovered from coma and uremia and survived. Chlorpromazine and Thiorazidine intoxications are reviewed with particular attention to the possible kidney damage.

Adult↗
PubMedDate not supplied

[Viagra: oral therapy of male erectile dysfunction I].

Sildenafil, the active component of Viagra was synthetized in 1992-3 and registered for sale in US and subsequently in Europe in 1998, on the basis of positive results of numerous preclinical and clinical studies. In the first part of this review, male sexual impotence (recently named erectile disfunction) is defined and its history and epidemiology is reported. The anatomy, physiology and biochemistry of erectile disfunction and the cycle of male sexual response are also discussed.

Enzyme Inhibitors↗