Neurohypophysial peptides in opiate withdrawal and tolerance.
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Animals↗
Biomedical subjects
E Markó
Publications and source records attributed to E Markó.
Development of acute morphine tolerance in peripheral clinico-chemical parameters.
Changes in peripheral clinico-chemical parameters packed cell volume (PCV), hemoglobin (HGB), serum glucose, carbamide-nitrogen (CN), and creatinine were investigated in mice during the development of acute morphine tolerance. Acute morphine treatment (in drug-naive organism) altered the PCV, HGB, serum glucose and CN levels in a naloxone-reversible manner. Acute tolerance developed in PCV, HGB and CN values. The data raise the possibility of a relationship between clinico-chemical and pharmacological tolerance.
Animals↗
Peripheral clinico-chemical parameters in experimentally naive versus morphine tolerant mice: evidence for development of clinico-chemical tolerance.
Changes in peripheral clinico-chemical parameters (packed cell volume (PCV), hemoglobin (HGB), serum glucose, carbamide nitrogen (CN), sodium, uric acid and creatinine) were investigated in mice during the development of acute morphine tolerance. Acute morphine treatment (in drug-naive organism) altered the PCV, HGB, serum glucose and CN levels in a naloxone-reversible manner. Acute tolerance developed in PVC, HGB, sodium and CN values. The data raise the possibility of a relationship between clinico-chemical and pharmacological tolerance.
Animals↗
Acid-base parameters in morphine tolerance.
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Acid-Base Equilibrium↗