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Biomedical subjects

E Markgraf

Publications and source records attributed to E Markgraf.

At least 19 recordsLinked to original sources

[The Marjolin's ulcer": a malignant and rarely complication after burn trauma of the upper extremity - a case report].

The,Marjolin's ulcer" is a malignant lesion which is developed especially at chronic wounds after burn trauma. The latency from primary trauma to the malignant transformation is about 30 years. The lesion is more aggressive than other squamous cell carcinomas. We report on the combined radiation and surgical therapy of an 65-year-old patient with this lesion on the right hand and regional lymph node metastases. The extensive tissue defect after wide excision was reconstructed with a reversal radial forearm flap.

Aged↗

[Injuries and being injured. Hidden wounds after accident injuries].

Motor vehicle accidents may cause apart from physical also psychological aftermath. Despite of posttraumatic psychologic symptoms may remit after 2-3 months, 10-20% of the injured persons will develop sustainable psychopathological symptoms. This report aims at an overview on possible psychopathological disturbances and their perpetuating conditions. Possible treatments are shown and the necessity of an interdisciplinary cooperation with the aim of a secondary prevention is emphasized.

Accidents, Traffic↗

[Pelvic injury].

Explore the source record for details and available documents.

Fracture Fixation↗

[Fibrolipomatous hamartoma of the nerve--a rare etiology of macrodactyly. A case report].

Fibrolipomatous hamartoma of nerve is a rare, tumor-like fibro-fatty growth arising from the epi- and perineurium. It mainly affects peripheral nerves and the median nerve in particular. An association with Klippel-Trenaunay syndrome and macrodactyly has been described. We present a 30-year-old patient, in whom the diagnosis of Klippel-Trenaunay syndrome had been made at the age of two, based on macrodactyly of the right hand. Because of increasing functional limitation and pain, the patient was referred to our department, after angiographic exclusion of Klippel-Trenaunay syndrome, for operative reduction of the tumor. Histologic examination revealed a fibrolipomatous hamartoma of the nerve. Further treatment consisted of surgical tumor reduction, which resulted in satisfactory recovery of function in the right hand. After eight months follow-up, the patient was able to perform all normal daily activities, and there was no evidence of recurrence of the lesion. Diagnostic evaluation of macrodactyly is necessary, since there may be an underlying cause such as fibrolipomatous hamartoma of a nerve, which if corrected early by surgical excision may prevent long-term disability.

Adult↗

[Joint empyema].

Bacterial joint infection is rare but may have an unfavourable functional aotcome. The different stages of purulent arthritis, depending on the pathophysiological developments, require different treatment measures. Clinical examination, analysis of joint tap and arthroscopy are crucial for diagnosis. Surgical management comprises: (1) open or arthroscopic débridement with intensive flush lavage; (2) postoperative drainage and flush lavage; (3) early and continuous active and passive motion. Recovery will be complete only if therapy is instituted as early as possible (within 3 days). Joint empyema must therefore be treated as a surgical emergency.

Adult↗

[Late outcome of severed extensor tendons in the area of the hand and fingers].

In the care and further treatment of patients with hand injuries, a necessary requirement of the hand surgeon is that he be able to cope with the interlocking factors that are no longer influential, for example, the type and extent of the trauma or the age of the patient; the influential factors are a thought-out care plan, atraumatic action with regard to optimal restoration of the hand. This also showed a retrospective analysis of results and post-examination from flexor tendon injuries in the hand of 298 patients, who were surgically cared for from 1984 to 1994 at the surgical clinic of the University of Jena. Of the 298 patients 119 patients with 198 flexor tendon injuries (165 fingers and 33 thumbs) were followed up. For objective assessment of the treatment results, the assessment scheme Buck-Gramcko was used.

Adolescent↗

[Traumatic peripheral vascular injuries].

2-4% of vascular injuries need operative reconstruction. In polytraumatized patients the rate is even 10%. Arterial vascular repair should precede venous reconstruction and orthopaedic stabilization due to limb threatening ischemia. Penetration or blunt vascular trauma result either in acute blood loss, ischemia or compartmental compression. Reperfusion syndrome leads to vital threat of patient. Clinical assessment, measurement of limb pressures using a Doppler device and use of duplex ultrasonography are reliable adjuncts in the rapid evaluation. Arteriography is rarely indicated and should be spared for patients with abnormal physical examination. Minimizing ischemia (6-8 h) is an important factor in maximizing limb salvage. Vascular repair include direct anastomosis or lateral suture repair mostly combined with primary shortening of the extremity. In most cases autogenous vein graft is required. Rethrombosis, arteriovenous fistula and pseudoaneurysms are possible complications. Stabilisation of the fracture has priority over vascular reconstruction. The initial steps to success are surgical debridement, adequate bony stabilization mostly by external fixation, revascularisation of vascular injury, immediate fascial decompression and early soft-tissue reconstruction. The best results are obtained when a multidisciplinary approach is used combining expertise in orthopedic surgery, vascular surgery and plastic surgery.

Arteries↗

[Analysis of primary management of bladder malfunction in traumatic paraplegic patients].

UNLABELLED: Intermittent catheterisation is the demanded therapy of bladder paralysis during the spinal shock. We investigated the realisation of this concept. In 1994 after first treatment in other hospitals 97 patients were treated in the Thuringian Spinal Cord Centre Sülzhayn. The primary treatment of the paralysed bladder was: indwelling catheter: 44 patients (45.4%), suprapubic catheter: 30 patients (30.9%). Only 15 patients (15.5%) were catheterized intermittently. No urological treatment was carried out in seven cases. CONCLUSION: The primary treatment of bladder analysis in spinal cord injured patients has to be improved.

Adult↗

[Therapy of soft tissue injuries--biological strategies].

The traumatic soft tissue injury plays a central role in fracture healing. The knowledge of pathophysiological mechanisms has completely changed the management and therapy of injuries accompanied by soft tissue lesions. Treatment is aiming for prevention of the circle of hypoxia, microvascular perfusion disturbance, increased membrane permeability and potential infections. General therapeutic principles are decontamination, debridement, revascularisation and decompression. Modern methods of soft tissue treatment take these principles into consideration.

Debridement↗

[Functional fracture treatment of the upper arm].

Using a functional brace, we treated 67 patients who had a fracture of the humeral shaft over a 5-year period from 1987 to 1992. We analysed several parameters of the fractures to discover those which influence healing. Desault, plaster cast or traction were used before applying a brace in an average time of 15 days. The osseous consolidation was 10 weeks in the average. The functional results were very good and good in 78.3%, acceptable in 18.3% and poor in 3.4% of the cases. Twelve humeral-shaft fractures were associated with a radial nerve palsy. Every patient recovered a full radial nerve function under the treatment with a functional brace. The retentive management of an operative treatment of humeral-shaft fractures associated with a nerve injury can be supported because of our experience.

Adult↗

[Trauma in elderly patients].

The increasing proportion of old and very old people in the population has increased the task of treatment in the field of surgery and its main points. The decreasing function of and changes to the skeleton caused by osteoporosis have led to a number of fractures. The fracture near the hip joint is typical for this section of the population. 1180 patients from the Jena surgical clinic/casualty were analysed; the average age was over 75 years and the most common cause of accident was a fall. A quick operative treatment is recommended. In comparison with the risk factor of the ASA-classification 1.6% with factor I and 44.4% with factor IV died. Postoperative treatment is very important.

Accidental Falls↗