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Biomedical subjects

E Marni

Publications and source records attributed to E Marni.

At least 19 recordsLinked to original sources
PubMed1992

Balloon nitinol device: a new possibility for the fixation of balloons in large arteries.

We propose a balloon with nitinol needles for the closure of large vessels avoiding the risk of embolisation. To demonstrate the possibility of application, we utilised a prototype consisting of a polyurethane balloon with one nitinol needle which reached the shape for securing the balloon to the vessel wall after changing the temperature of the device. If further research and experimentation in animals are favorable, it will be possible for the interventional cardiologist to occlude large vessels and perhaps intracardiac shunts easily without danger of embolisation.

Alloys↗
PubMed1988

Birth defects in the Seveso area after TCDD contamination.

A study on the frequency of birth defects was conducted in the area around Seveso, Italy, which was contaminated by 2,3,7,8-tetrachlorodibenzo-p-dioxin in July 1976; this has been the largest population ever exposed to dioxin. From Jan 1, 1977, to Dec 31, 1982, a total of 15,291 births (still and live) were examined, and malformations were reported to an ad hoc birth defects registry. In the most highly contaminated area, 26 births were observed. None of these infants had any major structural defect. Two infants had mild defects. The frequencies of major defects detected in the areas of low or very low contamination were 29.9/1000 and 22.1/1000, respectively. A frequency of 27.7/1000 was registered in the control area. Relative risks were calculated for specific categories of birth defects and for grouped malformations. Although the data collected failed to demonstrate any increased risk of birth defects associated with 2,3,7,8-tetrachlorodibenzo-p-dioxin, the number of exposed pregnancies was not big enough to show a low and specific teratogenic risk increase.

Accidents, Occupational↗
PubMed1984

[The apex cardiogram in normal aged subjects].

In 25 healthy subjects aged 60-88 years (mean 74.5) and in 20 healthy subjects aged 16-32 years (mean 23.6) apexcardiographic indices were studied as a function of age. The apex cardiograms (ACG) were obtained using a non-calibrated displacement transducer. With the help of an interactive computer program, 17 ACG indices of systolic and diastolic function were computed. The indices were divided into 2 groups (according to the nomenclature proposed by their Authors): a) systolic indices: electromechanical ventricular interval q-C, systolic upstroke time C-E, time from the beginning of ventricular depolarization to the peak of the first ACG derivative q-dA/dt, time from the onset of systolic slope to the peak of first ACG derivative C-dA/dt, ejection fraction according to Antani et al. 1979 E.F.; b) diastolic indices: electromechanical atrial interval P-a, atrial wave length d.a., height of atrial wave as percent of total ACG deflection a/H, height of atrial wave as percent of total diastolic deflection a/D, ratio of the diastolic wave to the total ACG height D/H, total rapid filling cR, early filling period EFP, rapid filling period RFP, total apexcardiographic relaxation time TART, duration of diastolic period A2-C, total apexcardiographic relaxation time index TARTI and diastolic amplitude time index DATI. Several diastolic indices (a/D, a/H, TART, electromechanical atrial time) were markedly higher (p less than 0.001) or lower (TART and DATI, p less than 0.001) in the older group. Systolic indices showed less significant differences: the electromechanical interval lengthened in the older group (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1984

[Comparative clinical evaluation of left ventricular ejection time using carotid and ear pulses].

The aim of this study was to verify if in the clinical use the relationship between the morphology of the carotid pulse and of the ear densitogram was constant enough to validate the measurement of left ventricular ejection time from the ear densitogram. In 92 subjects, aged 5-84 years, carotid pulse and ear densitogram were simultaneously recorded. The ear densitogram was electronically processed with 3 different filters, in an effort to duplicate the carotid pulse and thus to facilitate the measurements of the ejection time. Mean ejection time was 265.5 +/- 24.87 msec. for carotid pulse, and 265.7 +/- 24.19, 265.2 +/- 24.25, 266.2 +/- 24.78 for the ear densitographic methods. Analysis of variance did not show any differences among the 4 methods. We conclude that quite a constant relationship between carotid pulse and ear densitogram is present in clinical measurements. Thus, the carotid pulse can be reliably substituted by the ear densitogram.

Adolescent↗
PubMed1983

Angiosarcoma of the heart: report of a case in a 9-year-old boy.

A 9-year-old boy with a myocardiac angiosarcoma is described; the tumor was diagnosed by echocardiography and the boy underwent surgery followed by radio and chemotherapy. Death occurred 5 months after surgery, probably due to abdominal hemorrhage from metastases. The young age of the patient, the acute and reversible hepatic damage, the use of echocardiography for diagnosis and the possible role of the extracorporeal circulation in determining the metastases are emphasized.

Child↗
PubMed1983

Pulmonary arteriovenous fistulas: an unusual complication of congenital hepatic fibrosis.

A 16-year-old boy with congenital hepatic fibrosis, on whom a portocaval anastomosis was performed because of bleeding esophageal varices, developed lip cyanosis, exertional dyspnea, and clubbing of the fingers 7 years postoperatively. This progressive syndrome was caused by a right-to-left shunt due to the presence of pulmonary arteriovenous fistulas. Increased erythrocyte sedimentation rate, hypergammaglobulinemia, and histological features of cholangitis were also present. It is proposed that this unusual pulmonary complication of congenital hepatic fibrosis could be due either to congenital pulmonary abnormalities or to a chronic unrecognized cholangitis causing a progressive deterioration of liver histology and function, with subsequent opening of pulmonary arteriovenous shunts.

Arteriovenous Fistula↗
PubMed1980

Experiences from the accident of Seveso.

Provisional data on selected sanitary events which took place at Seveso after July 10 1976 are reported. 187 cases of chloracne, mostly in children, were detected, 50 just after the accident, the others within a year. Most polluted area (zone A) provided almost all "early" and most severe cases, but the territorial distribution of chloracne prevalence rates showed some inconsistencies with the soil TCDD pollution map; interpretations for such findings are discussed. Thirty-eight birth defects were detected in 1977 (none in zones A and B), more than in previous years, but still less than expected in a well controlled "normal" population: no clustering around a given type was observed. Spontaneous abortions, evaluated both as abortion rates and as pregnancy loss rates, showed scattered and statistically non-significant variations, inconsistent with the pollution map. No differences in birth and death rates compared to surrounding areas were observed. Data on ad hoc cytogenetic, neurological and immunological surveys are commented. Limitations of the presently available data are discussed and further research lines are anticipated.

Abnormalities, Drug-Induced↗