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Biomedical subjects

E Martínez-Castillo

Publications and source records attributed to E Martínez-Castillo.

4 recordsLinked to original sources

[Electromyographic response associated with capsular stroke].

INTRODUCTION: Lesions of the pyramidal system are characterized by their effects on qualitative aspects of movement. One of the features of pyramidal defects is the presence of associated movements or synkinesis. CLINICAL CASE: We present a case with residual associated electromyographic (EMG) response in a patient who had had a capsular stroke 11 months previously. The patient presented with acute onset of a syndrome of purely motor right hemiparesis (PMH) which improved satisfactorily with complete functional recovery three months later. Eleven months after the acute episode, there was good functional recovery and neurophysiological examination showed the presence of EMG responses associated with the unaffected limb (left hand) when voluntary movements were made with the right hand. CONCLUSION: The appearance of qualitative alterations of movement associated with pyramidal syndromes and particularly the presence of associated EMG responses in the case of capsular infarct described, may reflect the different processes of reinnervation and functional reorganization which occur following the lesion and which are involved in recovery of motor function.

Acute Disease↗

[Psychometric validation of the telephone memory test].

INTRODUCTION: Several pathologies (i.e. Alzheimer's disease) that courses with memory alterations, appears in a context of impaired cognitive status and mobility. In recent years, several investigations were carried out in order to design short batteries that detect those subjects under risk of dementia. Some of this batteries were also design to be administrated over the telephone, trying to overcome the accessibility limitations of this patients. METHODOLOGY: In this paper we present a battery (called Autotest de Memoria) essentially composed by episodic and semantic memory tests, administered both over the telephone and face to face. This battery was employed in the cognitive assessment of healthy controls and subjects diagnosed as probable Alzheimer's disease patients. RESULTS: Results show the capability of this battery in order to discriminate patients and healthy controls, a great sensibility and specificity, and a nearly absolute parallelism of telephone and face to face administrations. CONCLUSION: These data led us to claim the usefulness and practicality of our so called < >.

Aged↗

[Atrophy of the amygdala complex and neuropsychiatric expression of Alzheimer s disease].

INTRODUCTION: In Alzheimer s disease, together with cognitive changes (loss of memory, lack of orientation in time and space, difficulty in carrying things out, etc.) non cognitive disorders also occur, seriously disturbing the patient s behavioral and emotional balance. Depression, delirious ideas, hallucinations and behavior changes (habits regarding sex, feeding and movement) are amongst the commonest features of this disease from its earliest stages. Several studies have described how initially the histopathological changes selectively involve different structures of the medial temporal lobe ( entorinal cortex, hippocampal formation, amygdala) and gradually includes neocortical association areas. Thus, the amygdala complex, a structure related to processes of memory and emotional control, is severely affected in this disease from the initial stages. PATIENTS AND METHODS: Therefore, to find any possible relationship between involvement of the amygdala and the psychiatric expression of Alzheimer s type dementia, we did a radiological study, using magnetic resonance, together with a neuropsychological study of a group of 24 persons with Alzheimer s disease who had mild moderate deterioration. Analysis of the amygdala area and the scores on the subtest Alzheimer s Disease Assessment Scale Non cognitive (ADAS NC) were the variables chosen for measurement of the anatomical and psychiatric aspects of the subjects under investigation. RESULTS AND CONCLUSIONS: The results of our study show a close relation between involvement of the amygdala (atrophy) and the presence of neuropsychiatric changes in persons with Alzheimer s disease.

Aged↗