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Biomedical subjects

E Matouschek

Publications and source records attributed to E Matouschek.

At least 19 recordsLinked to original sources

[Dose uncertainties in irradiation of bladder cancer with the Nd: YAG laser beam].

By in vitro investigations with the laser set medilas 2 YAG (MBB) possible dosage insecurities were demonstrated in the radiation of urinary bladder cancers using Nd-YAG-laser light. While the endoscopic distance of e.g. 3 +/- 1 mm is accompanied by a relatively low dosage uncertainty of +/- 23%, the thermic formation of gas bubbles on the endoscopic end area, which is immersed in flush fluid, may be cause a dosage uncertainty of 80%. Help is possible by slipp off the endoscope area on the bladder wall. Uncertainties because of different tissue absorption of radiation are not taken into account.

Cystoscopy

[Experimental studies in transurethral, intravesicular ultrasonographic research].

The investigations were performed via a 7.5 MHz transurethral rotating ultrasonic probe. The axial and lateral resolution was determined. The experiments for the determination of the thickness of the bladder wall and for the discrimination between the different types of tissue were carried out by means of pig's bladders and biological specimen. A certain and reproducible discrimination of the different tissue layers and an exact determination of the thickness of the bladder wall were not possible due to the missing single echoes of the boundary interfaces and to the dependence of ultrasonic image structures on the selected amplification. Additionally, the speckled structures of the ultrasonic images have a magnitude of millimetres and render the discrimination very difficult between tumour tissue and bladder wall tissue. We would require signal processing by computer to obtain an exact resolution of the signal information.

Animals

[The influence of uric acid on the calcium oxalate stone formation (author's transl)].

Statistic analysis of data from 209 calcium oxalate stone patients and 42 stone-free patients pertinent to the concentration and excretion of uric acid in urine and of uric acid levels in the serum yielded no significant difference between the two groups. Only 17% of the calcium oxalate stone patients suffered from hyperuricuria and hyperuricemia was found only in 15% of these patients. Based on these findings, our in-vitro experiments as to the influence of uric acid on calcium oxalate stone formation yielded the following results: firstly, precipitates in urine form only at uric acid concentrations which in-vivo are rate exceptions humans, and secondly, the precipitates at pH 5.5--6.0 always contain uric acid, and a precipitation of calcium oxalate only is never observed. From the experiments one has to conclude that there exists no "salting-out effect" of uric acid on calcium oxalate in urine but rather that precipitate formation reflects the individual solution- and crystallization characteristics of the precipitating compounds.

Calcium Oxalate

[The application of video techniques in urology (author's transl)].

Above all Videosystems have valuable applications in transurethral surgery for students, housestaff and established physicians in that they allow for better documentation and communication. This article describes a handy, inexpensive color T. V. camera which, though one of the smallest and lightest, produces good quality pictures. The paper also describes various applications of such a system.

Education, Medical, Continuing

[The conservative therapy of urolithiasis (author's transl)].

Some common conservative treating methods of urolithiasis are critically discussed. Based on physico-chemical relationships of solubility and cristallisation of stone-forming compounds our own methods of conservative treatment of urolithiasis is presented.

Allopurinol

Internal urethrotomy of urethral stricture under vision--a five-year report.

This report deals with experience with the method of transurethral incision of urethral strictures under vision in 547 patients involving 662 internal urethrotomies between Nov. 1972 and Aug. 1977. Follow-up examinations showed good results in 79, 3% of the patients. Transurethral incision of urethral strictures can be recommended as the method of choice for the treatment of urethral strictures.

Adult

Quantitative element investigations in urine, serum, kidney and muscle tissue of calcium oxalate stone patients.

Concentration and excretion in 24-hour urine, as well as serum concentrations of Na, K, Mg, Ca, Cl, P, uric acid and citrate were investigated in 209 calcium oxalate stone patients and 42 stone-free patients. Especially the concentration values of the urine components, except for uric acid and citrate, were found to be significantly lower for calcium oxalate stone patients. 21% of the stone patients showed hypercalciuria; hypercalciuria combined with hyperuricuria was found in only 7.1% of the cases and a solitary hyperuricuria in only 17%. As for kidney cortex, kidney papilla and muscle tissue in 10 calcium oxalate stone patients and 10 stone-free patients, the concentrations of Na, K, Ca, Mg as well as some trace elements were determined quantitatively by means of neutron activation analysis. Statistic analysis yielded a significantly lower sodium content of the kidney cortex within the stone-carrying group. Mean values of the calcium concentration in stone patients were lower for papilla and muscle tissue than in the control group. For magnesium no clear differences were found. The iron content in the papilla and muslce tissue of stone patients was significantly lower.

Calcium

[Reservoir for bacteria of urinary tract infections in urologic patients (author's transl)].

Many infections of the urinary tract, especially after surgical treatment are nosocomial infections. The etiological bacteria could only be found in the urine of the infected patients and in the faecal flora of nearly 40% of all stationary patients. The so called "problem bacteria": Klebsiella, Proteus rettgeri, pseudomonas showed increasing drug resistance during the observed period between 1972-1975. The bacteria isolated from the faecal flora also showed multiple drug resistance. Thus we concluded that the antibiotic regime in these patients is very important for the selection and the increase of the problem bacteria both in urine and in the faecal flora.

Anti-Bacterial Agents

[Internal urethrotomy of urethral strictures in men under endoscopic control].

From November 1972 to October 1974 190 patients of the "Urologische Klinik der Städt. Krankenanstalten Karlsruhe" with urethral strictures were treated by internal urethrotomy under endoscopic control with the modified urethrotome from Stortz/Germany. This is a report about short-time results (2-14 months) after treatment. The method is very simple and the effect is controlled by endoscopy. In the first 44 patients we used general or lumbal anaesthesia. In the last patients only local anaesthesia by Instillagel installation into the urethra was used. The short-time results were excellent in 66.8%. We believe that this method points out a new direction in the surgical treatment of urethral strictures.

Adult

[Conservative therapy of urolithiasis].

Some common conservative treating methods of urolithiasis are critically discussed. Based on physico-chemical relationships of solubility and cristallisation of stone-forming compounds our own methods of conservative treatment of urolithiasis is presented.

Crystallization