Biomedical subjects

E Matysiak

Publications and source records attributed to E Matysiak.

4 recordsLinked to original sources

PubMed1992

[Changes in CSF resorption resistance. Experimental studies].

Lumbar infusion tests (IT) with different infusion rates (0.06 ml/min-1.2 ml/min) were used in order to investigate the intracranial pressure (ICP) and CSF outflow resistance (R) changes. Two groups of animals were studied: control group and animals with an 0.8 ml epidural balloon. In control group (without balloon) significant differences in ICP and R values between the increasing and decreasing IT curve were found. The most pronounced changes were noticed right after the highest infusion rate (40% for ICP value and 49% for R value). The results in the balloon group were very similar and the only difference were delayed ICP and R changes. The results obtained suggest that the determined R values are specific for the applied infusion rate and this phenomenon has to be taken into account in all human studies.

Animals↗

PubMedDate not supplied

[Changes of visual evoked potentials in experimental occlusion of superior sagittal sinus in the cat].

In the model of experimental occlusion of superior sagittal sinus (SSS) in 6 cats, the authors examined cerebral cortex activity by means of visual evoked potentials (VEP). They found shortening of latency of P2 wave potential in relation to the control by 5.5-13.3 msec, appearing after 4-6 hours following occlusion. Simultaneous cerebrospinal fluid pressure measurement indicated an increase in pressure following SSS occlusion from the control medium value 6.8 mmHg to 12-13 mmHg. Visual cortex in cat (area 17) is situated along the posterior portion of SSS. The occlusion of this vessel results in local haemostasis, which is likely to affect the physico-chemical properties of visual cortex cells, especially in the slow conducting system X (X cells can be found exclusively in area 17). The partial disappearance of this system activity results in reducing the signal and noticeable shortening of latency to peak P2 wave of VEP.

Animals↗

PubMedDate not supplied

[Analysis of the correlations of volume-pressure parameters and visual evoked potentials during disturbances of intracranial volume compensation].

The experiment was carried out on 19 cats with changed intracranial volume-pressure relations by means of an epidural balloon which was inflated to 1.0 ml volume over 60 minutes. The intracranial pressure, the resistance to cerebrospinal fluid resorption, the volume-pressure responses and visual evoked potentials were determined at balloon volumes of 0.3 ml, 0.5 ml, 0.8 ml, 1.0 ml, 1.3 ml, 1.5 ml, 1.8 ml, 2.0 ml and 2.3 ml. It was demonstrated that intracranial pressure is of important informative value only after exhaustion of 63% of the intracranial volume reserve. This value of the volume-pressure responses and resistance to CSF resorption appeared after exhaustion of 28% of this reserve, and the visual evoked potentials were changed after exhaustion of 43% of the reserve. The correlation coefficient between these parameters was high during decompensation. At the time of compensation of the volume the correlation coefficient between the intracranial pressure and the remaining determined parameters was only 0.6.

Animals↗

PubMedDate not supplied

[Changes in the intracranial volume-pressure relations and visual evoked potentials produced by stabilized and compensated additional volume].

The experiment was carried out on 17 cats with intracranial volume-pressure relations changed by means of an epidural balloon of 1.0 ml volume (group I--12 cats) and 0.5 ml (group II--5 cats). The duration of compression exerted by the balloon was 360 min. The intracranial pressure, volume-pressure responses, resistance to cerebrospinal pressure resorption and visual evoked potentials were determined at intervals of 60 minutes. In group I pressure exerted by 1 ml balloon was followed by changes of volume-pressure relations and visual evoked potentials which increased with duration of the experiment. In group II the changes were noted only in the volume-pressure responses and resistance to CSF resorption at the time of balloon volume rise from 0 to 0.5 ml. Maintenance of this balloon volume in the cranial cavity caused no further changes of volume-pressure parameters or visual evoked potentials during 360 minutes of the experiment.

Animals↗