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Biomedical subjects

E Mayr

Publications and source records attributed to E Mayr.

At least 37 records · Page 2Linked to original sources

Ultrasound--an alternative healing method for nonunions?

Several years ago, low-intensity pulsed ultrasound (frequency 1.5 MHz; signal burst width 200 micros; signal repetition frequency 1 KHz; intensity 30 mW/cm2) was shown to accelerate fresh fracture healing both clinically and experimentally. On the basis of a prescription use registry, this paper reports on the use of low-intensity pulsed ultrasound in the therapy of 951 delayed unions and 366 nonunions. The overall success rate for delayed unions was 91% (average healing time 129+/-2.7 days) and for nonunions 86% (average healing time 152+/-5.3 days). Stratifying the data, it becomes clear that patient medication with calcium channel blockers, non-steroidal anti-inflammatory drugs, and steroids is a negative predictor for healing nonunions, as well as renal or vascular insufficiency. Patients who were smokers during ultrasound therapy had lower healing rates than those who never smoked. When comparing the patients of our own clinic treated with low-intensity ultrasound under study conditions which demonstrate that if healing was achieved it was an effect of the ultrasound therapy to the worldwide prescription use registry, no difference was seen in healing rate, healing time, or fracture age. Therefore, the results of these two populations support each other. Low-intensity pulsed ultrasound may provide a method of nonoperative treatment of great promise for healing disorders. Determination of ranking of this new method should be done within the near future.

Adult↗

The unreamed tibia nail. Multicenter study of the AO/ASIF. Osteosynthesefragen/Association for the Study of Internal Fixation.

In the last 10 years, traumatologists have become more aware of the importance of blood supply to fracture fragments for both the healing of fractures and prevention of infection. Due to our experience with fractures having severely disrupted periosteal blood supply, we are looking more critically at intramedullary reamed nailing as a treatment option. This research was a result of our increased knowledge of the interplay between periosteal and endosteal blood supply.

Adolescent↗

[Does low intensity, pulsed ultrasound speed healing of scaphoid fractures?].

Since pulsed low-intensity ultrasound (frequency: 1.5 MHz, pulsed by 1 kHz, signal burst width: 200 microseconds, intensity: 30 mW/cm2) has been proven to stimulate fracture healing both clinically and experimentally, our question was whether this therapy also accelerates healing of fresh stable scaphoid fractures. Addressing this question, we did the following prospective randomized clinical trial. Regarding the results of former clinical fresh fracture studies by Heckman and Kristiansen, we postulated that low intensity ultrasound accelerates healing by about 30%. Based on this thesis, we calculated that 30 patients divided into two groups would be necessary to show significant differences between the standard treatment (treated by casting) and an adjunctive ultrasound treatment (treated by casting and additional daily 20 minutes ultrasound treatment) if present. Diagnosis and healing was assessed by CT scans every two weeks. CT's were analyzed by two independent radiologists and one hand surgeon. Furthermore, areas of cancellous bone bridging in correlation to the diameter of the scaphoid was measured in each CT scan. The results showed ultrasounded fractures healing in 43.2 +/- 10.9 days versus 62 +/- 19.2 days in the control group (p < 0.01). Trabecular bridging six weeks after injury showed 81.2% +/- 10.4% healed in the ultrasound-stimulated fractures versus 54.6% +/- 29% in the control (p < 0.05). Our study results confirm those of Heckman and Kristiansen and show a similar acceleration of bone healing. Low intensity ultrasound is successful in accelerating the healing of fresh scaphoid fractures.

Adult↗

[Pseudarthrosis].

Understanding the pathophysiology of non-union is a prerequisite for successful treatment of this disorder. Fracture healing may be impeded by mechanical or biological factors as well as a combination of these. A thorough evaluation of each individual case before surgery is necessary to prevent either undertreatment or overtreatment. The whole spectrum of methods of internal fixation may be utilized for stabilization. To optimize the biological component, classic methods such as decortication and cancellous autograft may be employed. It is too early yet to determine if alternative techniques (e.g. ultrasound) will successfully replace these long-standing options. In any case, these newer modalities cannot supplant the need for skeletal stabilization. For infected pseudarthroses the first step is eradication of infection, after which measures can be taken to unite the fracture. Callus distraction has opened new and safe ways to treat large bone defects.

Biomechanical Phenomena↗

[Ultrasound therapy for nonunions. Three case reports].

Despite of the good results of operative treatment disorders of fracture healing are still a challenge for surgeons. In some cases all endeavours are frustrating and bone does not heal. Low intensity pulsed ultrasound (frequency: 1.5 MHz, pulsed by 1 KHz, signal burst width: 200 musec, intensity: 30 mW/cm2) offers the opportunity of an alternative treatment. In contrast to magnetic field therapy, electric stimulation or use of extracorporal shock waves this therapy is judged positively all over the literature. Within an own series of 76 cases at present time we can show a 86% healing rate under defined conditions. Within this paper we present three case reports, which clearly show the efficiency of low intensity pulsed ultrasound.

Female↗

[Treatment of acromioclavicular joint separations. Central Kirschner- wire and PDS-augmentation].

Beside the basic question wether a separation of the acromioclavicular joint should be treated operatively or not, the method of operation is discussed in particular. For that reason we investigated our own method of a temporary transfixation of the joint by a centrally drilled K-wire combined with a PDS-augmentation of the coracoclavicular and a suture of the acromioclavicular ligament. Follow up examinations were possible in 57 out of 82 patients which were operated during 5 years. Patients subjective rating and objective follow up and sonographically evaluated joint conditions were scored together. Looking for the range of motion of the shoulder only 5.5% of the patients had a reduction of more than 20 degrees. Out of 12 complications in particular three infections only resulted satisfying by influencing the subjective rating negatively. In 28.1% of patients no durable anatomic reconstruction of the joint was achieved. Score achieved by these patients was significantly lower compared to those with a lasting anatomic reconstruction of the acromioclavicular joint. In conclusion the results confirm our operative regime for separations of the acromioclavicular joint. In literature survey the here described method of operation belongs to the better ones without showing a clear advantage. Nevertheless the method should be modified to decrease the rate of subluxations.

Acromioclavicular Joint↗

[Late results after fracture of the femoral head].

The dislocation fracture of the femoral head is the result of high speed trauma. Most of the patients have additional injuries. The prognosis of this kind of fracture of the femoral head depends on the type of fracture, the additional injuries and the age of the patients. The diagnosis and the specific treatment are most important, since most of the patients with this injury are of a younger age. The reposition of the fracture has to be performed within 6 hours. In our opinion, this should be done by surgery if possible. For the operation some routine pelvic X-rays and a CT of the pelvis should be prepared. The therapy depends on the type of fracture. In patients with Type I and II fractures the broken head fragments should be refixed by only taking out small parts of bone which are not elementary for the pressure zone of the femoral head. Younger patients with Type III fractures should always receive the possibility of a screw fixation of the neck of femur, whereas total hip replacement should generally be achieved in the older patient. An exact reconstruction of the dorsal acetabulum must be performed in Pipkin Type IV fractures. The usual approach for Type I-III fractures is the ventrolateral Smith-Peterson and lateral Watson-Jones, for Type IV fractures, the dorsal Kocher-Langenbeck approach. We suggest indometacine as a prophylaxis for ossifications due to high tissue damage. Several scores for the evaluation and documentation of the outcome of this kind of fracture are useful: the clinical results according to Merle d'Aubigne, social status scored by the Karnofsky Index and X-ray results using Brooker and Helfet to classify the heterotopic ossification and post traumatic joint changes.

Adolescent↗

The efficacy of using search engines in procuring information about orthopaedic foot and ankle problems from the World Wide Web.

This study has attempted to demonstrate the feasibility of obtaining information specific to foot and ankle orthopaedics from the World Wide Web (WWW). Six search engines (Lycos, AltaVista, Infoseek, Excite, Webcrawler, and HotBot) were used in scanning the Web for the following key words: "cavus foot," "diabetic foot," "hallux valgus,"and "pes equinovarus." Matches were classified by language, provider, type, and relevance to medical professionals or to patients. Sixty percent (407 sites) of the visited websites contained information intended for use by physicians and other medical professionals; 30% (206 sites) were related to patient information; 10% of the sites were not easily classifiable. Forty-one percent (169 sites) of the websites were commercially oriented homepages that included advertisements.

Ankle↗

[Reconstruction of complex acetabular fractures using the extensile kocher-langenbeck approach (modified maryland approach).].

GOAL OF SURGERY: Approach to the essential bony parts of the pelvis which can be adapted to the fracture pattern and which causes minimal soft tissue damage. It allows exposure of the posterior and anterior columns and the roof of the acetabulum. INDICATIONS: Complex acetabular fractures such as 2-column fractures, T-fractures, displaced transverse fractures with posterior rim fragment, fractures of 1 column. CONTRAINDICATIONS: Fractures which can be approached through smaller incisions, preexisting lesions of the superior gluteal artery, arterial occlusive diseases, particularly of the pelvis. PREOPERATIVE WORK UP: Radiographs of the pelvis in anterior-posterior and two oblique news. Special radiographs and CT. POSITIONING AND ANAESTHESIA: Lateral decubitus with free draping of the leg. Endotracheal anaesthesia. Cell saver optional. SURGICAL TECHNIQUE: T-shaped skin incision and gradual extension of the Kocher-Langenbeck approach depending on the fracture pattern. First extensile step: Transverse division of the fascia lata and osteotomy of the greater trochanter. Second extensile step: Osteotomy of part of the iliac crest and exposure of the outer and inner cortex of the iliac wing. POSTOPERATIVE MANAGEMENT: Operated leg rests in a foam padded splint. Careful wound drainage, routine low dose radiation or indomethacin to prevent heterotopic ossification. CPM starting the 2nd postoperative day, mobilization starting the 2nd or 3rd day with partial weight bearing of 15 kg. Full weight bearing depends on fracture type and consolidation. POSSIBLE COMPLICATIONS: Delayed wound healing with risk of infection. Injury to the superior gluteal artery with danger of necrosis of the abductor muscles. Injury through stretching of the sciatic nerve. Injury of the lateral femorocutaneous nerve. RESULTS: Seven patients with complex acetabular fractures were operated between June 1993 and January 1994. Use of the 1st extensile step was sufficient in 3 patients and 3 times all 4 steps were used. Postoperative necrosis of fatty tissue necessitated 2 revisions. All fractures consolidated. During the follow-up examination 1 case of heterotopic ossification was seen (Brooker grade II). Using the classification of Merle D'Aubigné we had 1 excellent, very good, 2 good and 1 satisfactory result.

English Abstract↗