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Biomedical subjects

E McCartney

Publications and source records attributed to E McCartney.

27 records · Page 2Linked to original sources

Experimental infection of piglets with cryptosporidium.

Piglets from five litters were doses orally with cryptosporidium originally derived from diarrhoeic calves. The piglets were either nursed by the sow, artificially reared after sucking colostrum, or weaned on to creep feed. Colostrum-fed, artificially reared piglets obtained from two litters and exposed in the first week of life developed clinical signs of inappetence, vomiting and diarrhoea and shed oocysts in the faeces. Histologically the parasite was observed throughout the small and large intestine attached to epithelial cell surfaces and its presence was associated with extensive mucosal damage, particularly in the posterior small intestine, stunting and fusion of villi, immaturity of villous epithelial cells and oedema with increased cellularity of the lamina propria. Piglets from two other litters, both sucking and colostrum-fed artificially reared, exhibited similar but milder clinical signs. Histological lesions were less severe and cryptosporidium infection less extensive. When weaned piglets were exposed they remained clinically healthy although histologically there was evidence of cryptosporidium attachment in the small intestine and minor mucosal damage. There appears to be a good correlation between the extent of intestinal infection, the degree of mucosal damage and the severity of clinical disease induced by cryptosporidium in piglets.

Animals↗

A study of the hearing and receptive vocabulary of the trainees of an adult training centre.

Hearing and receptive vocabulary (E.P.V.T. full-range version) of the trainees of an adult training centre have been studied. A high incidence of hearing loss (47.1 per cent) was found. The correlation between receptive vocabulary and hearing loss was significant at the five per cent level for the adult Down syndrome subjects in the study. Recommendations are made on the services required, particularly with reference to audiology, that could significantly contribute to the reduction in the number of hearing-impaired mentally handicapped subjects who are at present in hospital care.

Acoustic Impedance Tests↗

Proliferative haemorrhagic enteropathy.

This study indicates that viable Campylobacter sputorum subsp mucosalis are not present or are present in small numbers in the mucosa of pigs dying of proliferative haemorrhagic enteropathy. The changes present in the mucosa are similar to those seen in pigs recovering from adenomatosis and the evidence obtained indicates that the intracellular organisms observed in this condition are indeed mucosalis. The presence of large amounts of IgA in the altered tissue of both proliferative haemorrhagic enteropathy and porcine intestinal adenomatosis indicates that the failure to recover bacteria may be immunologically mediated but is not simply related to the presence or absence of antibody in the respective conditions.

Animals↗

Barriers to collaboration: an analysis of systemic barriers to collaboration between teachers and speech and language therapists.

A systems approach is used to examine the barriers to collaboration found in the working practices of speech and language therapists and teachers. Functional, structural and systems-environment barriers are found, but few process barriers, which may explain why good collaborative practice can be found in the field. The differences that serve as barriers are listed and discussed, with a view to fostering mutual understanding between teachers and speech and language therapists.

Humans↗