Suicidal behavior by hospitalized preadolescent children on a psychiatric unit.
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Adolescent↗
Biomedical subjects
E McCauley
Publications and source records attributed to E McCauley.
Correlation between serum and salivary cortisol levels in depressed and nondepressed children and adolescents.
Serum and saliva cortisol levels were determined in 34 depressed and nondepressed children and adolescents. The serum and salivary measures were highly correlated. The measurement of salivary cortisol may be a useful noninvasive technique in the study of cortisol secretion patterns in young subjects.
Adolescent↗
Follow-up of females with gender identity disorders.
The present paper reports on the course of 15 young female-to-male transsexual applicants followed for 1 to 9 years after initial evaluation. Each patient completed a lengthy evaluation process including detailed semistructured interviews and a battery of psychological tests. Of the 15 applicants, 10 went on to live full time in the male role; however, one of these later returned to living as a female. This woman and three others were living as lesbians at last follow-up, while the two other patients continued to live in a more ambiguously male-female role. Psychosocial functioning at the time of follow-up in terms of employment, partners, and psychiatric status is reviewed. A supportive problem-solving psychotherapy program was offered to all of these patients and seven became actively involved in therapy. The potential benefits and limitations of psychotherapy with female gender dysphoric patients are discussed.
Adolescent↗
Inhibition by prostaglandins of leukotriene B4 release from activated neutrophils.
Chemoattractant N-formylmethionylleucylphenylalanine (fMet-Leu-Phe) in the presence of cytochalasin B stimulates the release of leukotriene B4 (LTB4), superoxide (O2-), and N-acetylglucosaminidase from elicited rat peritoneal and human peripheral neutrophils [PMN (polymorphonuclear leukocytes)]. Prostaglandins E1 and E2 (PGE1 and PGE2) inhibit LTB4 release from PMN in a dose-related manner with an IC50 of 1 X 10(-8) M. This action is associated with increased levels of cyclic AMP. The inhibitory activity of a variety of PGs on LTB4 production by rat peritoneal PMN parallels their affinity for PGE receptors in other tissues. O2- release is also suppressed by low levels of PGE1 and PGE2 in a dose-related manner and this inhibition is enhanced by theophylline. In contrast, lysosomal enzyme release is only minimally affected by physiological levels of PGs. These data are consistent with an action of PGs at the level of the PG receptor on LTB4 and O2- release from the fMet-Leu-Phe-stimulated rat peritoneal PMN. In addition, the fMet-Leu-Phe-induced adherence of PMN to endothelial cells and inhibition of this phenomenon by PGs may now be explained by PG-mediated inhibition of LTB4 formation.
Alprostadil↗
Female s-xual response. Hormonal and behavioral interactions.
Recent studies suggest that hormones do play a role in the expression of female sexual behavior, and the inconsistency of findings between various groups does not mean that hormonal effects can be disregarded. Hormones may interact with other situational variables to sometimes enhance sexual behavior, and at other times suppress it. Sexual activity may itself trigger alterations in hormone levels, just as hormones may activate changes in behavior.
Coitus↗