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Biomedical subjects

E Meroni

Publications and source records attributed to E Meroni.

35 records · Page 2Linked to original sources
PubMed1991

Esophageal intubation for malignant fistulas.

Between April 1978 and December 1989 at the Endoscopy Division of the National Cancer Institute of Milan, 140 patients were intubated for esophageal neoplasms; 19 of these subjects underwent endoscopic intubation for malignant fistulas complicated by pneumonia and/or mediastinitis. The prostheses were tolerated well and enabled the restoration of oral nutrition. The mean survival was 4.7 months (range, 0.5-17 months). No major complications occurred. Tube dislodgement was observed in 2 cases (10.5%). Two patients died of causes that were not related to the procedure.

Aged↗
PubMed1991

Pharyngo-esophageal prostheses in malignancies of the cervical esophagus.

Cervical location of inoperable esophageal carcinoma is usually considered a contraindication of palliative intubation due to technical limitations and complications of the procedure. Between 1978 and 1989, 32 patients with inoperable cancer of the cervical esophagus were treated endoscopically at the Endoscopy Division of the National Cancer Institute, Milan. Eight of them underwent endoscopic intubation. The prostheses were tolerated well and did not cause any respiratory impairment. No complications related to the procedure were observed. In seven of the patients resumption of oral nutrition led to improvement of the general condition. The mean survival time was 5.5 months (range 0.5-23 months).

Aged↗
PubMed1990

Esophageal tumors--treatment by endoscopic intubation.

Esophageal tumors are often inoperable, because of the poor general condition of patients or the coexistence of metastatic disease. Endoscopic intubation is a safe method of palliation in these patients which can restore esophageal patency and lead to an improved nutritional status. At the Endoscopy Division of the National Cancer Institute in Milan, 141 patients with inoperable esophageal cancer underwent endoscopic intubation between 1978 and 1989. The 7-day mortality was 9/141 (6.3%) patients. In 114/132 surviving patients there was an improvement in the nutritional status and general condition. The complication rate was 17.7% (25/141 patients) and the mean survival was 5.9 months.

Adult↗
PubMed1988

Endoscopic dilation of the cystic duct.

In a case of gallbladder and common bile duct lithiasis, the selective cannulation of the cystic duct and gallbladder by a balloon catheter after endoscopic papillosphincterotomy fulfilled both diagnostic and therapeutic purposes. A choledochal stone was retrieved with the Dormia basket. The endoscopic dilation of the cystic duct by the balloon permitted spontaneous elimination of all the gallbladder stones.

Adult↗
PubMed1987

Gastric submucosal neoplasms: new diagnostic and therapeutic procedures.

Submucosal neoplasms can be found in the esophagus and stomach during radiologic or endoscopic examination; histological diagnosis, however, is not significant in many cases because sampling is difficult. Endoscopic biopsies usually do not allow to obtain tissue from the submucosal layer nor other techniques prove to be reliable enough. 23 patients, aged between 21 and 76 were studied over a period of 5 years; in 1 male large gastric folds were observed. Of the 22 patients affected by benign submucosal neoplasms, 2 underwent surgical operation; no significant samples were obtained in any of the 11 cases in which biopsy forceps had been used. In the remaining patients an electrosurgical snare for polypectomy was used; this technique proved to be successful in 77.8% of cases. It is often shown to be also a therapeutic method when polypoid neoplasms are found.

Adenocarcinoma↗
PubMedDate not supplied

Significance of the clonal and sporadic chromosome abnormalities in non-neoplastic renal tissue.

Trisomy 7, trisomy 10 and loss of the Y chromosome have been found by some authors in presumptive normal parts of human kidneys. We describe cytogenetic findings in short-term cultures from 58 biopsies obtained from non-neoplastic and neoplastic (renal cell carcinoma, RCC) tissues from the same kidney, the same types of tissues from independent kidneys, and tissue from kidneys without neoplasia. The results indicate the following. Non-neoplastic tissue from kidneys involved in RCC have (in mosaics) trisomies 5, 7, 10, 18 and loss of the Y as non-random clonal changes. They are not the result of local metastasis but are also found in kidneys with non-tumoral chronic pathologies and should thus not be considered specific for RCC. They are neither culturing artefacts nor a general phenomenon found in cultured normal solid tissues, but are acquired abnormalities, possibly related to various reactive cellular states in the tissues that are histologically normal.

Adult↗
PubMedDate not supplied

Two-step endoscopic resection of gastric leiomyomas.

Our two-step technique for endoscopic treatment of gastric leiomyomas is illustrated. From January 1979 to June 1991, nine symptomatic patients with sessile leiomyomas of the stomach were treated at the Endoscopy Division of Istituto Nazionale Tumori, Milan. The diagnosis was achieved by means of endoscopic observation of the lesion and, when possible, by ultrasound endoscopy. This new technique consists of first removing superficial portion of the tumor by electrosurgical snare. Second, a cleavage plane is found within the proper muscle layer; the tumor is enucleated as much as possible by tightening the snare around it and creating a pseudo-stalk. No major complication occurred nor were any recurrences observed at 21.8 months in the 7/9 patients treated by endoscopy alone. Endoscopic therapy was performed on an outpatient basis and only large lesions required short hospitalization.

Adult↗
PubMedDate not supplied

Endoscopic stent placement for cancer of the lower esophagus and gastric cardia.

We reviewed our results of using stents for palliation of cancer of the lower third of the esophagus and gastric cardia. During a 14-year period, 76 patients with either lower third esophageal cancer (n = 43) or cancer of the gastric cardia (n = 33) received stents for palliation of malignant dysphagia. Successful endoscopic placement was initially achieved in all patients, with 71 patients available for follow-up. Of these, 40 (56%) were subsequently able to eat solid or semi-solid food, 25 (35%) could swallow only liquids, and 6 (8%) were unimproved. The combined early and late complication rate totalled 22%. Early complications included perforation (n = 3) and stent migration (n = 4); late complications consisted of dislodgment (n = 6), obstruction by tumor (n = 2), and severe esophagitis (n = 1). There were no procedure-related deaths, but survival at 1 year was estimated to be only 1.5%, with a median survival of 2.5 months after stent insertion. The endoscopic placement of prosthetic stents for cancer of the distal esophagus and gastric cardia entails a higher complication rate, less successful palliation, and shorter survival time compared to similar treatment for more proximal esophageal cancer.

Aged↗
PubMedDate not supplied

[Metal prostheses].

Explore the source record for details and available documents.

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