PubMed Health⌕ Search

Biomedical subjects

E Mevio

Publications and source records attributed to E Mevio.

50 records · Page 3Linked to original sources
PubMed1984

Polygraphic study of vestibular stimulation in epileptic patients.

Vertigo, vestibular function and the effect of labyrinthine stimulation on the EEG were studied in 29 epileptic patients. Vertigo has no distinguishing characteristics and the epileptic nature of this symptom can be only tentatively inferred from its chronological relationship with the other epileptic features. In a high percentage of epileptic subjects, especially those with focal seizures, abnormal vestibular responses can be observed. This finding may be ascribed to the existence of a common cerebral lesion responsible for both focal seizures and vestibular abnormalities, even though the data do not allow us to exclude the role played by antiepileptic treatment in modifying the vestibular response. Caloric labyrinthine stimulation in the method employed by us shows a limited activating effect on the EEG and clinical epileptic pattern. Even in the positive cases this method does not allow us to reach any precise anatomo-physiological conclusions.

Adolescent↗
PubMed1983

IgM and IgD concentrations in the serum and secretions of children with selective IgA deficiency.

Serum IgG and serum and secretory IgM, IgA and IgD levels were determined in 14 children with selective IgA deficiency and in 12 age and sex matched healthy controls. IgD was determined using a highly sensitive ELISA technique. In the healthy controls serum IgG, IgA and IgM were all in the age normal range, and serum IgA was significantly higher than secretory IgA with IgA in nasal secretions being significantly higher than in saliva. In the IgA deficient children serum IgG and IgM and secretory IgM were present in higher concentrations than in the controls but the difference was statistically significant only for serum IgG and salivary IgM. IgD was detectable in the serum and secretions of all patients and all but one control subject. Like IgM, serum IgD levels were significantly higher than secretory IgD levels and IgD was present in greater concentrations in nasal secretions than in saliva both in the patients and the controls, with no difference between the two groups. Thus, the data of this study show that while serum and secretory IgM levels are elevated in children with selective IgA deficiency, serum and secretory IgD are present in normal concentrations, supporting the hypothesis of a compensatory increase in IgM but not in IgD in such patients.

Adolescent↗
PubMed1983

[Tranexamic acid in the prevention of oropharyngeal radiomucositis].

The therapeutic effect of tranexamic acid in prevention of radiomucositis has been evaluated in a double blind study. The results suggest that tranexamic acid can be the useful for the treatment of radiomucositis in head and neck cancer patients submitted to radiotherapy.

Cyclohexanecarboxylic Acids↗
PubMed1982

Oculomotor abnormalities after labyrinthine and cerebellar lesion. A case report.

A subject presenting a rare association of left labyrinthine and left hemispheric cerebellar lesion was examined, with recording and analysis of eye movements at different intervals. A complete compensation of the vestibular deficit and recovery of cerebellar postural ataxia, with persistence of limb incoordination and oculomotor abnormalities, were observed. The saccadic, smooth pursuit and optokinetic nystagmus systems were impaired. Ocular signs, in combination, may suggest a cerebellar dysfunction but they do not supply sufficient diagnostic criteria for localizing the cerebellar damage. Only the direction-specific impairment of smooth pursuit and optokinetic nystagmus is indicative of the side of the lesion.

Ataxia↗
PubMed1981

Impaired suppression of vestibular nystagmus by fixation of visual and acoustic targets in neurological patients.

Suppression of vestibular nystagmus induced by fixation of visual and acoustic targets moving with the head during sinusoidal rotation (0.1 Hz, 75 degrees/second peak velocity) was tested in cerebellar and noncerebellar patients. Visual suppression was impaired greatly in cerebellar patients, without correlation with visual smooth-pursuit defects. Acoustic suppression was equal to or slightly weaker than visual suppression. In noncerebellar patients, a disturbance of visual suppression was found only in the presence of a severe impairment of pursuit eye movements. Acoustic suppression did not parallel the visual-suppression pattern. In clinical vestibular examination, an impaired modulation of the vestibulo-ocular reflex suggests a cerebellar dysfunction, but also can occur in the presence of disorders of other parts of the CNS severely affecting the SP system.

Attention↗
PubMedDate not supplied

Proliferative characteristics of head and neck tumors. In vivo evaluation by bromodeoxyuridine incorporation and flow cytometry.

Cell proliferation of head and neck cancers was studied in 52 patients using in vivo bromodeoxyuridine (BUDR) incorporation. Patients received 250 mg BUDR intravenously several hours prior to biopsy of the tumor tissue. Bivariate flow cytometry was used and enabled us to rapidly obtain DNA ploidy, labelling index (LI), DNA synthesis time (TS) and tumor potential doubling time (Tpot). This method was found to be suitable to obtain complete cytokinetic data in 46/52 (88.5%) patients. The mean BUDR LI was 7.9% (range 2-18%); mean TS was 11.6 h (range 6-28.5 h); mean Tpot was 5.7 days (range 2-30 days). BUDR LI and TS were significantly correlated with histological differentiation grading: G3 tumors showed higher LI values and shorter TS values than G1/G2 tumors. A similar correlation was found between LI or TS and tumor dimensions. Tpot was also significantly lower in larger tumors, such as in those with a higher grading. No significant correlation was found between LI or TS and DNA ploidy (50% of the tumors in our series were DNA aneuploid), while Tpot was found to be 10 days in diploid tumors, compared to only 6.3 days for the aneuploid tumors (p < 0.05). All cases with documented lymph node involvement (N+) showed significantly higher LI, and shorter TS and Tpot values if related to nodal free ones (Tpot = 10 days in N+ patients and 6.3 days in N- patients; p < 0.05). The results of this study suggest that the method employed is clinically feasible and could be a useful aid in defining the prognosis of head and neck cancer patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenocarcinoma↗
PubMedDate not supplied

Harmonic versus impulsive acceleration testing of the vestibulo-ocular reflex in normal humans.

Vestibulo-ocular reflex (VOR) was tested in 9 normal humans by using both harmonic (sinusoidal) and impulsive (post-rotatory) angular accelerations. VOR gain and main time constant were 0.49 +/- 0.20 and 15.48 +/- 2.26 s, respectively, when computed from sinusoidal responses, 0.45 +/- 0.17 and 14.28 +/- 3.07 s when computed from impulse responses. Paired comparison could not prove statistically significant differences between the two sets of data. The conclusion is drawn that, in normals, equivalent information about VOR static and dynamic characteristics can be derived from either harmonic acceleration or post-rotatory tests.

Acceleration↗
PubMedDate not supplied

[Anaerobic cervical cellulitis: a therapeutic approach].

The possibility of life-threatening complications arising from cervico-facial infections is well known. Deep cervical infections, however, rarely spread to the mediastinus. Organisms responsible for these infections usually include either aerobic or anaerobic microorganisms, whose synergistic activity provokes virulence and contributes to the violent nature of infection. Prompt recognition is vital if appropriate treatment is to be given. Initial management of deep-neck infections consists in intensive parenteral antibiotic therapy. Nevertheless, in spite of antibiotic therapy, mortality due to suppurative mediastinitis remains high. The Author emphasizes the importance and gives priority to surgical drainage and debridement, another fundamental part of treatment.

Adult↗