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E Muñoz

Publications and source records attributed to E Muñoz.

323 records · Page 18Linked to original sources
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[The fluorimetric determination of dabequin in biological fluids].

A study of dabequin was performed to define its possible quantification by spectrofluorimetry. By this technique, dabequin was shown to present maximum excitation and emission wave length at 400 and 450 nm, respectively. Drug emission was determined at different concentrations of sulfuric acid and no changes were observed. Two quantification procedures are compared to determine, which one produces better results in quantifying total serum and blood levels in patients. Specificity of a thin-layer chromatography method, as well as the drug stability in 0.05 M sulfuric acid medium are shown.

Aminoquinolines↗
PubMedDate not supplied

Clinical experience with cefotaxime (HR-756) in surgical patients.

Twenty adult surgical patients aged between 15 and 83 years (mean:45), 10 of whom had wound infections (one complicated with septicaemia), 2 with septicaemia, 1 with gynecological infection complicated with endocarditis, 5 with urinary tract infections and 2 with lower respiratory tract infections, were treated with parentally-administered cefotaxime. Aetiology was Proteus 7, E. coli 4, Pseudomonas 3, Enterobacter 2, Klebsiella 2 and 2 Serratia. Susceptibility testing was determined by the agar dilution method, with MIC values ranging from 0.01 to 5 microgram/ml, with two urinary isolates of Pseudomonas with MIC of 20 microgram/ml. Clinical responses were excellent in 13 (65 per cent) cases, moderate in 2 (10 per cent) and 3 (15 per cent) failed to respond to therapy. Clinical assessment was not possible in three patients. Bacteriological responses were excellent in 14 (70 per cent) cases, poor in 4 (20 per cent) and in two there was no follow-up. Systemic tolerance was good in all patients except one.

Adolescent↗
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Usefulness of antral brushing samples stained with Diff-Quik in the cytologic diagnosis of Helicobacter pylori. A comparative methodologic study.

We studied the usefulness of antral cytologic specimens obtained by brushing and stained with Diff-Quik in the diagnosis of gastric colonization by Helicobacter pylori in 102 patients, comparing this method with other commonly employed techniques. We report on the sensitivity, specificity, predictive value for positive and negative cases of each of the techniques used, and diagnostic problems posed by each. In general, the Diff-Quik-stained samples proved to be the most useful. This technique is a simple, economical and practical method for the diagnosis of gastric colonization by H pylori.

Biopsy↗