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E Munoz

Publications and source records attributed to E Munoz.

At least 55 records · Page 3Linked to original sources

Effects of the heavy usage of kava on physical health: summary of a pilot survey in an aboriginal community.

Health status was assessed in 39 kava users and 34 non-users in a coastal Aboriginal community in Arnhem Land. Twenty (27%) respondents were very heavy (mean consumption, 440 g/week) users of kava; 15 (21%) respondents were heavy (310 g/week) users of kava and four (5%) respondents were occasional (100 g/week) users of kava. Kava users were more likely to complain of poor health and a "puffy" face, and were more likely to have a typical scaly rash, and slightly-increased patellar reflexes. Very heavy users of kava were 20% underweight and their levels of gamma-glutamyl transferase were increased greatly. Albumin, plasma protein, urea and bilirubin levels were decreased in kava users, and high-density lipoprotein cholesterol levels were increased. Kava users were more likely to show haematuria, and to have urine which was poorly acidified and of low specific gravity. The use of kava was also associated with an increased red-cell volume, with a decreased platelet volume and with a decreased lymphocyte count. Shortness of breath in kava users was associated with tall P waves on a resting electrocardiogram, which provided suggestive evidence of pulmonary hypertension. In common with other Aboriginal communities, there was evidence of decreased lung volumes, a high carriage rate of hepatitis B surface antigen, and of other morbidity that was unrelated to the use of kava. On the basis of these findings, there is a strong rationale for urgent social action to improve health in Aboriginal communities and, in particular, to reduce the consumption of kava and to improve the nutritional status of kava users.

Adolescent↗

Financial risk, hospital cost, complications and comorbidities (CCc) in non-CC stratified urology diagnostic related groups.

The federal Medicare Diagnosis Related Group payment mechanism is undergoing constant change. Significant interest has been generated at the health policy level regarding reimbursement for patients with complications and comorbidities. The purpose of this study was to analyze hospital resource consumption for patients in the seventeen urology non-complicating condition (CC) stratified Diagnostic Related Groups (DRGs), currently 45 percent of urology DRGs. We analyzed 185 Medicare patients in these non-CC stratified urology DRGs and found that patients with more CCs per patient had higher total hospital costs per patient, financial risk under DRGs, a greater percentage of outliers, and a higher mortality, than patients in these same DRGs with fewer CCs per patient. These findings suggest that the current DRG system is inequitable to some patients and certain hospitals vis-a-vis non-CC stratified urology DRGs. The Health Care Financing Administration has not significantly changed the complicating condition urology DRG classification, as of its recent May, 1988 legislation. Financial disincentives to treat these patients may affect both their access and quality of care in the future.

Centers for Medicare and Medicaid Services, U.S.↗

Financial risk, hospital cost, complications, and comorbidities in surgical noncomplication- and noncomorbidity-stratified diagnostic related groups.

The purpose of this study was to analyze resource consumption in the 147 non-complicating condition-stratified surgical diagnostic related groups (DRGs). Analysis of 2647 surgical patients in these non-CC-stratified surgical DRGs demonstrated that patients with more CCs per DRG generated higher total hospital costs, a longer hospital length of stay, a greater percentage of procedures per patient, financial risk under DRG payment, more outliers, and a higher mortality rates than patients in these same DRGs with fewer CCs. These findings suggest that the current DRG classification system may be inequitable to certain groups of patients or types of hospitals vis-à-vis the non-CC-stratified surgical DRGs. Financial disincentives to treat these patients may affect both their access and quality of care in the future.

Academic Medical Centers↗

Surgonomics: the costs of ruptured abdominal aortic aneurysm.

Surgical care costs continue to rise at a rate greater than overall U.S. economic growth. Government and industry have vowed to slow the growth of health care spending. Prospective payment systems using the Diagnostic Related Group (DRG) mechanism are being phased in for payment of in-patient hospital care. One expected effect of the DRG payment scheme is a more careful financial analysis of the components of surgical care. The purposes of this study were to examine a vascular procedure, ruptured abdominal aortic aneurysm (RAAA), performed at a large teaching hospital during a ten-year period; to characterize patients by cost (hospital charges exclusive of physician fees) and outcome; and to test the hypothesis that an IDENTIFIER, here the presence or absence and duration of hypotension (less than 90 mm Hg systolic), could predict differences in cost and outcome. The results, in conjunction with historic data, were used to quantify aggregate hospital expenditures for this condition by survivor and the identifier. The results indicate: (1) mortality is higher for the hypotensive patient than for the normotensive patient (p less than 0.05) and is related to the duration of hypotension; (2) lowest mean charges per patient were in the hypotensive more than thirty minutes group ($5,587) followed by normotensive ($28,298), then hypotensive less than thirty minutes ($43,876); and (3) the mean charges for each survivor were $42,447 for normotensive patients versus $107,572 for hypotensive patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

DRGs, orthopedic surgery, and age at an academic medical center.

The federal Medicare Diagnostic Related Group (DRG) hospital reimbursement system has been on line for 5 years. Hospitals contend that profit margins have dropped to dangerously low levels, due to the federal DRG Prospective Payment System. The authors analyzed all orthopedic surgical admissions to a large academic medical center under DRG reimbursement and characterized patients by age, resource utilization, and outcome. Total costs for the 1,040 orthopedic patients analyzed during a 15-month period added up to $9,718,800. Mean hospital cost per patient, mean hospital length of stay, percent outliers, and mortality generally increased with age. All age categories of patients 65 years of age and above generated financial losses under DRGs. Older orthopedic patients consumed a disproportionately larger share of resources than younger patients, and were more frequent users of the SICU and blood. The current DRG reimbursement scheme may be inequitable in relation to the older orthopedic surgery patient. If these findings are demonstrated at other medical centers, older orthopedic surgical patients could be limited in both their access and quality of care in the future.

Academic Medical Centers↗

Financial risk, hospital cost, and complications and comorbidities (CCs) in non-CC stratified neurosurgical diagnostic related groups (DRGs).

The purpose of this study was to analyze hospital resource consumption in the nine neurosurgical DRGs not stratified by complicating condition (CCs) (i.e., those neurosurgical DRGs that give no additional payment for associated medical conditions or complications occurring in the hospital). We analyzed 148 Medicare patients in these non-CC stratified neurosurgical DRGs and found that patients with a greater number of CCs had higher hospital resource consumption, substantial financial risk under DRGs, and a poorer outcome than patients with no CCs. These data suggest that the current DRG classification scheme may be inequitable vis-à-vis the non-CC stratified neurosurgical DRGs at our hospital. Hospitals that treat significant numbers of these patients may face disincentives to care for them under prospective Medicare DRG reimbursement.

Blood Transfusion↗

Hospital costs, resource characteristics, and the dynamics of death for hospitalized gastroenterology patients.

The federal Medicare diagnosis-related group (DRG) hospital payment system has been on-line for 5 yr with no major adverse effects on either access or quality of care. The hospital industry contends that DRGs are underpaying for hospital care, especially for certain types of patients. Analysis of 2,500 gastroenterology patients by outcome (i.e., survivors vs mortalities) demonstrated that the 122 mortalities had a much greater intensity of hospital resource utilization, and generated substantial financial risk under DRG pricing schemes, compared with the 2,378 survivors. Only mortalities that occurred within 1 wk of admission to the hospital were profitable under DRGs. A long hospital length of stay (LOS) for mortalities was very unprofitable (mortalities with more than a 60-day LOS generated $20,210 loss per patient). Emergency gastroenterology admissions who died had greater financial risk under DRGs, compared to nonemergency mortalities. Those mortalities referred to gastroenterology from other clinical services tended to have greater resource utilization and financial risk under DRGs, compared with nonreferred mortalities. These data suggest significant inequities in the current DRG prospective payment system vis-a-vis gastrotenterology mortalities. Predictive variables of greater hospital resource utilization for gastroenterology mortalities include longer hospital lengths of stay, emergency admission, and referral from another clinical service. If equity of DRG payment is not improved by the federal government, certain groups of patients likely to be mortalities may suffer a decline in access and/or the quality of medical care in the future.

Adult↗

Are routine preoperative laboratory screening tests necessary to evaluate ambulatory surgical patients?

Two hundred twelve consecutive adult patients undergoing a variety of ambulatory surgical procedures were studied prospectively to investigate whether routine preoperative urinalyses, complete blood counts (CBCs), and electrocardiograms (ECGs) were useful in determining the outcomes of their treatments. Urinalyses (U/As) were abnormal in 83 patients (39%); CBCs were abnormal in 19 patients (9%), and ECGs were abnormal in 140 patients (66%). The mean age of the patients was 64 plus or minus 12 years. The majority of patients with abnormalities determined by laboratory tests could have been predicted to have abnormalities on the basis of their histories and physical examinations. In this study, abnormalities indicated by laboratory tests did not influence preoperative cancellations, intraoperative or postoperative complications, or admissions to the hospital from the ambulatory unit after the surgical procedures. We conclude that routine preoperative screening laboratory tests have only a limited value in ambulatory surgical patients and recommend that they be either eliminated or replaced with less costly studies; for example, dipstick urinalyses for urinalyses, spun hematocrits for CBCs, and ECGs should be performed only if indicated by history and physical examination findings or if requested by an anesthesiologist.

Aged↗

The effects of postoperative factors on serum thyroid hormones and rat liver nuclear 3,5,3'-triiodothyronine receptor concentrations in surgical models of uremia and regenerating liver.

We have determined the individual effects of postoperative fasting, surgical/anesthetic factors, acute uremia (AU), and regenerating liver (RL) on nucleoplasmic (NP; 0.15 M KCl-extractable) and chromatin-bound (CB; 0.4 M KCl-extractable) rat liver T3 receptors. AU and RL rats were studied 24 h after bilateral nephrectomy (blood urea nitrogen, 128 +/- 13 mg/dl) or two thirds hepatectomy, respectively. The effects of postoperative fasting were assessed by comparison of normal rats (N) with control rats (N6) pair-fed to match the caloric intake of the AU and RL rats. Surgical/anesthetic effects were determined by comparison of N6 rats with sham-operated pair-fed rats (S6). The effects of AU or RL were obtained by comparison with S6 controls. Changes in mean body weight attributable to fasting (N6-N), surgical/anesthetic effects (S6-N6), acute uremia (AU-S6), and regenerating liver (RL-S6) were: -17.3 (P less than 0.001), -4.0 (P = NS), -4.5 (P less than 0.05), and -1.0 g/24 h (P = NS), respectively. Changes in mean serum T4 (N, 5.3 +/- 1.3 micrograms/dl) were: -1.0 (P = NS), -0.6 (P = NS), -0.9 (P less than 0.05), and -1.0 micrograms/dl (P less than 0.05), respectively. Changes in mean serum T3 (N, 53 +/- 23 ng/dl) were: -8 (P = NS), -18 (P less than 0.05), -10 (P = NS), and -14 ng/dl (P less than 0.05), respectively. The NP and CB receptor pools of the AU and RL rats were not significantly different from those of age-matched N rats (NP, 25 +/- 5 fmol/mg DNA; CB, 405 +/- 134 fmol/mg DNA). Chronically uremic (CU) rats 2 weeks after five sixths nephrectomy (blood urea nitrogen, 36 +/- 2 mg/dl) did not exhibit significant change in their extractable receptor pools. Complete starvation for 24 h (NO) or 72 h (NOO) generally resulted in marked reductions in receptor concentrations compared to those in age-matched N rats fed ad libitum: NP pool (N, 31 +/- 17 fmol/mg DNA): NO-N, -40% (P = NS); NOO-N, -59% (P less than 0.01); CB pool (N, 303 +/- 105 fmol/mg DNA): NO-N, -19% (P less than 0.05); NOO-N, -41% (P less than 0.001). These studies indicate that severe AU, moderate CU, and LR have relatively little effect on solubilized rat liver nuclear receptor concentrations. In contrast, complete starvation is a potent depressant of both nuclear receptor pools. In the surgical models of AU and LR, postoperative fasting was the primary cause of weight loss.(ABSTRACT TRUNCATED AT 400 WORDS)

Animals↗

Early discharge of the postmastectomy patient: unbundling of hospital services to improve profitability under DRGs.

Cost containment is necessary for health care facilities to remain profitable and, therefore, operable. Thus, newer strategies of providing quality patient care need be developed to achieve this goal. The purpose of this study was to compare the costs and outcome of patients who had modified radical mastectomies, who were discharged home with an indwelling hemovac drain, and whose follow-up was conducted by visiting nurses in contrast to the traditional hospitalization of these patients until the hemovacs were removed. Two groups were compared in a prospective fashion. Twenty patients who had undergone a modified radical mastectomy for stage I or II breast carcinoma and who were discharged home with an indwelling hemovac drain (HWIH) were compared with 20 modified radical mastectomy patients who remained hospitalized with the drains for continuous wall suction (IHWH). Mean length of stay for the HWIH group (2.65 days) was significantly lower than the IHWH group (9.65 days) (P less than .001). Mean total hospital charges (exclusive of physician fees) were significantly lower for the HWIH group ($ 2106) than for the IHWH group ($ 7672) (P less than .001). Under Diagnosis Related Group (DRG) reimbursement allowances, the IHWH group had a loss of $ 355 per patient, whereas the HWIH group had a profit of $ 5211 per patient. One complication in the HWIH group required rehospitalization (a wound infection that was treated with IV antibiotics). This study suggests that significant improvement in efficiency may be accomplished for selected mastectomy patients who are discharged home with the indwelling hemovac drain to be followed as outpatients by both the surgeon and a nurse specialist.

Breast Neoplasms↗

Morphometric aspects of rat testis development.

A morphometric study of rat testis development and ageing (from 5 to 360 days of age) has been carried out. The testicular volume increases from 10.28 +/- 0.35 mm3 (5 days of age) to 1819.43 +/- 52.67 mm3 (360 days of age), showing the most rapid increase between 20 and 70 days of age (22.6 times). The mean tubular diameter increases from 62.25 +/- 1.50 micron (5 days of age) to 280.81 +/- 9.77 microns (360 days of age) and the tubular length from 2.74 +/- 0.18 m (5 days of age) to 25.45 +/- 1.76 m (360 days of age). Up to 15 days of age, the increase in testicular volume was mainly due to the increase in tubular length, whereas from this age onwards the tubular growth was similar in both length and diameter. Tubular development had nearly finished at 70 days of age.

Aging↗

Economic costs of trauma, United States, 1982.

The economic costs of trauma to the United States were analyzed by taking latest available data from United States Vital Statistics and using models to convert to dollar costs for trauma fatalities and nonfatalities. Trauma cost the nation approximately +61.025 billion dollars in fiscal 1982 (1977 figures indexed to 1982 dollars). This included +19.278 billion for direct costs (treatment related) and +41.746 billion in indirect costs (forgone earnings). The largest single category by group was indirect costs (forgone earnings) for male fatalities (+26.635 billion). The next largest was direct costs (treatment related) for male nonfatalities ($ 12.145 billion.) This disease is currently responsible in economic costs (1982 dollars) for 6.9% of health care expenditures and 2.3% of the United States gross national product (GNP).

Accidents, Traffic↗

Quantitative light and electron microscopic changes in thymic reticular epithelial cells during Moloney-virus-induced lymphoma development.

This report describes two types of reticular epithelial cell in the thymic cortex of the BALB/c mouse, an immature and a mature form. During early stages of lymphoma development, i.e., 2-6 weeks postinfection (p.i.) with Moloney leukemia virus (M-MuLV), activation of the epithelial cells is observed. Although the percentage of these cells in the total cell population of the thymic cortex remains constant during that time, the number of mature epithelial cells is significantly increased in infected animals. Subsequently, about 6 weeks p.i., the number of immature epithelial cells starts to increase, whereas the number of mature reticular epithelial cells declines and the appearance of the mature epithelial cells changes drastically. The results of light and electron microscopic studies indicate degeneration of the mature reticular epithelial cells at the onset of lymphoma development at a time when the first deficiencies in the immunologic competence of the reticular epithelial cells are apparent.

Animals↗

Surgonomics.

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Colloids↗