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Biomedical subjects

E Murillo Capitán

Publications and source records attributed to E Murillo Capitán.

7 recordsLinked to original sources
PubMed1994

[Protocols].

Explore the source record for details and available documents.

Clinical Protocols↗
PubMed1992

[Cervicobrachial fibromatosis presenting in the mother and the child simultaneously].

Fibromatosis is the proliferation of connective tissue with local infiltrative growth and a tendency to relapse in contrast with fibrosarcoma which never produces metastases. Two patients, a mother and son diagnosed with fibromatosis of initial cervical location in whom surgical extirpation and complementary radiotherapy were performed. The mother underwent polychemotherapy (adriamicine plus dacarbazine) because of extensive relapse. Definitive resolution was achieved in both cases.

Adolescent↗
PubMed1984

[Peripheral neuropathy produced by cisplatin].

The authors tell about one case of peripheral neuropathy of the upper limbs as a complication of cis-diaminedichloroplatinum. It is a rare complication that has to be diagnosed early to prevent invalidating damage.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

[Polychemotherapy treatment with cisplatin, adriamycin, 5-fluorouracil (FAP) and cisplatin, adriamycin and cyclophosphamide (CISCA) in advanced transitional carcinoma of the bladder].

We study 50 patients with advanced bladder carcinoma, divided into two protocols of 25 patients, treated with polychemotherapy. Protocol I (PAF) formed by DDP at 20 mgrs/m2 day 1 to 5, ADM at 50 mgrs./m2 day 1 and 5-FU at 500 mgrs./m2 day 1, and Protocol II (CISCA) made up of the combination of DDP at 75 mgrs./m2 day 1, ADM at 50 mgrs./2 day 1 and CPM at 600 mgrs./m2 I.V. day 1. In Protocol I the overall response was 60% (RC = 28%, RP = 32%), with amean response duration of 12.24 months, after receiving an average of 4.8 cycles. In Protocol II the results were 60% (RC = 16%, RP = 44%), 7.04 months and 5 cycles per patient, respectively. Both protocols were tolerated well, although Protcol I proved more toxic. Nauseas, vomiting and alopecia were the most common symptoms. There was no significant difference between the survival of responders and non-responders with Protocol I, but there was with Protocol II with (p less than 0.01).

Adult↗