PubMed Health⌕ Search

Biomedical subjects

E N Kazakov

Publications and source records attributed to E N Kazakov.

At least 37 records · Page 2Linked to original sources
PubMed1985

Experimental model of right ventricular failure with heterotopic heart transplantation for assisted circulation.

In 20 acute experiments on 40 mongrel dogs ranging in weight from 15 to 20 kg, a heterotopic heart transplant was implanted into the chest of the recipient with experimentally induced right ventricular failure. A detailed description is presented of the operative technique in acute and chronic experiments. Haemodynamic findings attest to the efficacy of the work of the transplant, the right ventricle of which is able to take over most of the work of the right ventricle of the recipient.

Animals↗
PubMed1975

[Surgical treatment of severe forms of ischemic heart disease].

Over 400 operations of an indirect revascularization of the myocardium have been performed at the A.I. Bakulev institute of Cardiovascular Surgery of the USSR Academy of Medical Sciences. Since 1970, the direct method have been developed, predominantly those of aorto-coronary bypass. Careful examination of 709 patients was carried out, 445 of them were subjected to selective coronary angiography, 108 were operated on. In 1974, 56 operations were undertaken, among them 36 aorto-coronary bypasses, in 6 of them with a preliminary endarterectomy from the coronary artery, 8 double bypasses, 6 procedures for acute myocardial infarction, 5 combined operations of aorto-coronary bypass and resections of cardiac aneurysms, and 15 resections of postinfarction aneurysms of the heart. Twelve patients died in the postoperative period, mainly due to acute cardiac insufficiency. The high figures of mortality are caused not only by the faults of the surgical procedures but also by the grave initial state of the patients (multiple coronary lesions large focal cardiosclerosis due to preceeding infarctions, high degree of initial cardiac insufficiency). The improvement of the results of surgery for the ischaemic heart disease will depend on the perfection of the surgical technique, on proper selection of the patients, and on the precise determination of the indications for such treatment.

Adult↗
PubMedDate not supplied

Evidence for antibody and immune-complex deposition in heart transplantation: a report of three cases.

Immunofluorescence microscopy of endomyocardial biopsy specimens from heart allograft recipients identified immunopathologic changes in three of 17 patients. These changes included immunoglobulin G and complement C3 deposition in tissue structures such as capillary endothelium and basal membranes, cardiomyocyte sarcolemma, and interstitial tissue. Moreover, the immunopathologic changes could be correlated with acute cellular rejection episodes evidenced by endomyocardial biopsy criteria.

Biopsy↗