PubMed Health⌕ Search

Biomedical subjects

E N Mercer

Publications and source records attributed to E N Mercer.

12 recordsLinked to original sources
PubMed1989

Doppler echocardiography in the evaluation of tricuspid stenosis.

Seventeen patients (12 with native and five with prosthetic tricuspid valves) with tricuspid stenosis were studied by Doppler echocardiography followed by cardiac catheterization within 24 h. The mean tricuspid diastolic pressure gradient was calculated using the modified Bernoulli equation. Tricuspid valve area (TVA) was calculated by the pressure half-time method (TVA = 190 divided by pressure half-time). Data from Doppler echocardiography and cardiac catheterization were compared. The Doppler-derived tricuspid mean diastolic gradient was 1.9-9.9 mmHg (average 5.3 +/- 2.5 mmHg), which correlated moderately well with the catheterization-determined mean diastolic gradient of 2-17 mmHg (average 7.3 +/- 4.0 mmHg), R = 0.74, standard error of the estimate (SEE) 1.70 mmHg, Y = 0.45 x + 2.00, P less than 0.001. The Doppler-derived TVA was 0.56-1.58 cm2 (average 1.06 +/- 0.32 cm2), which correlated well with the catheterization-determined TVA of 0.4-2.2 cm2 (average 1.06 +/- 0.46 cm2), R = 0.81, SEE = 0.20 cm2, Y = 0.56 x + 0.46, P less than 0.001. Of 12 patients undergoing right ventricular angiography, the angiographic and Doppler grades of tricuspid regurgitation matched exactly in six and differed by one grade in the remaining six. This study demonstrated that Doppler echocardiography compares very well to cardiac catheterization in the quantification of tricuspid stenosis and in the assessment of concomitant tricuspid regurgitation.

Adult↗
PubMed1987

Brucella endocarditis.

Brucella endocarditis is an underdiagnosed, fatal complication of human brucellosis. Four successfully treated cases of Brucella endocarditis are reported. The development of a new valvar lesion and bulky vegetations seen on echocardiography helped to identify Brucella endocarditis occurring during systemic brucellosis. The aortic valve was affected in all four patients, and in one the mitral valve was also affected. Medical treatment did not cure the patients and all needed valve replacement--for haemodynamic deterioration in three and because a further embolism was feared in one. Antibiotics were continued for six to nine months after operation. There was no early or late mortality and no recurrence after a follow up of 15 months.

Adult↗
PubMed1985

Endomyocardial fibrosis: report of eight cases.

Endomyocardial fibrosis is a disease of unknown origin which has not previously been described in detail from the Middle East. The clinical, echocardiographic, hemodynamic and angiocardiographic findings in eight patients (five men and three women, mean age 38 years) are presented. Two patients had right-sided involvement, two had left-sided involvement and four had biventricular involvement. The presence of a small ventricle with obliteration of the apex and a large atrium is a two-dimensional echocardiographic finding highly suggestive of endomyocardial fibrosis. Hemodynamic characteristics of dip and plateau on ventricular pressure curves were present in six patients. Ventricular angiography was diagnostic in all cases. Endomyocardial biopsy yielded positive findings in three of six patients and is not essential for diagnosis.

Adult↗
PubMed1970

Late systolic click in non-obstructive cardiomyopathy.

Two patients with seriously impaired left ventricular function, abnormal left ventricular conduction on the electrocardiogram, mitral regurgitation, and a very late systolic click are reported. Idiopathic non-obstructive cardiomyopathy seemed to be the cause of the left ventricular dysfunction in both cases. The mitral valve was anatomically normal at the time of operation in one patient, except for dilatation of the annulus, and the mitral regurgitation appeared to be secondary to left ventricular failure. The very late timing of the mitral systolic clicks in these two patients may be related to a large left ventricular end-diastolic volume and impaired left ventricular function, or to an abnormal sequence of excitation of the left ventricle. The timing of the late systolic click in these patients is in contrast to that in patients with mid systolic clicks, hearts of normal size, and little cardiac disability.

Angiocardiography↗