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Biomedical subjects

E N Ponomareva

Publications and source records attributed to E N Ponomareva.

At least 19 recordsLinked to original sources
PubMed1997

[The cerebellar cortical atrophy syndrome].

The results of the observation of 44 patients with cerebellar syndrome of different etiology are presented. Together with careful study of anamnestic and clinical data some additional examinations were performed: senso- and pallesthesiometry, thermovisional investigation, vestibulometry, electroencephalo-, electromyography, computer tomography. The study allowed to reveal both the cause of the disease and to refer etiologically late cerebellar cortical ataxia to alcohol factor. On the basis of the comparison of clinical neurological data with paraclinical observation differential diagnostic criteria were defined for Marie-Foix-Alajouanine's late cortical cerebellar atrophy in alcoholism, in the cases of the hereditary predisposition as well as of unclear genesis, in Holmes olivocerebellar atrophy, in Menzel, Hunt and Déjérine-Thomas olivopontocerebellar degeneration.

Adult↗
PubMed1996

[Chronic inflammatory demyelinating polyneuropathies].

A chronic inflammatory demyelinating polyneuropathy (CIDP) is described both on the basis of authors' own observations and literary data. The disease is characterised by delayed onset with progredient, progredient-remittent and stable course of flaccid paresis of extremity together with mild distal sensitive disturbances, albumino-cytologic dissociation and dysimmunoglobulinemia. Cranial nerves damages and vestibulo-cerebellar disturbances were observed in a number of patients. This confirms the involvement of CNS in CIDP. The common character of clinical, immunological, laboratory and electrophysiological findings permits to consider CIDP and Guillain-Barré syndrome as autoimmune diseases. Meanwhile some recent findings on the formation of antibodies to peripheral nerves structures as well as high titers of antisulfamide and antigangliosides antibodies permit to suggest CIDP as separate nosological unit. Additional clinical data and the evaluation of the role of etiological and pathogenetic mechanisms are necessary for the final conclusion.

Adolescent↗
PubMed1993

[Chronic herpetic encephalitis with a progressive epileptic syndrome].

Basing on the evidence provided by clinicomorphological and immunobiological studies, three, patients with progressive epileptic seizures were found to have chronic herpetic inflammation in the brain. The seizures took serial pattern with development of status epilepticus.

Adolescent↗
PubMed1992

[Clinical forms of acute herpetic infections of the central nervous system in adults].

The authors describe the course of herpetic encephalitis in 52 patients aged 16 to 64 years. Five types of the initial manifestations of herpetic infection of the CNS were revealed. In 44.3% of cases the disease started from the general cerebral symptomatology and consciousness disturbance; in 13.6% it started in a brain stroke-like manner followed by the development of the comatose status; in 13.6% of cases from memory disorder and unmotivated actions; in the same percentage of cases, the disease onset was marked by the dominance of dizziness, diplopia, ataxia and central hemiplegia ; in 15.9% the disease started from pains in the stomach, loin and lower limbs. Hemispheric and pseudotumorous stem encephalitides (48.1 and 13.6% respectively) were predominant; in 25% meningoencephalitides and in the remainder, encephalomyelitis running their course in the form of disseminated encephalomyelitis (5.7%), focal myelitis (5.7%) or opticomyelitis (1.9%). The data presented attest to the pleomorphism of the clinical picture of herpetic lesions of the CNS.

Acute Disease↗
PubMed1991

[A differentiated approach to the therapy of the Parsonage-Turner syndrome].

The authors have analyzed the anamnestic, clinical and laboratory data in 44 patients with Parsonage-Turner syndrome. Two forms of the disease were distinguished: radicular ischemia of vascular genesis, and the local form of infectious allergic polyradiculoneuritis associated with injury to the shoulder girdle of infectious genesis.

Adolescent↗
PubMed1990

[Neurologic semeiotics of Jakob-Creutzfeldt syndrome].

The paper is concerned with the results of a clinicomorphological analysis of 17 cases of Creutzfeld's-Jacob disease (CJD) in patients aged 39 to 78 years. The authors show polymorphism of the clinical manifestations at the early stages of the disease and the necessity of differentiation between atherosclerotic dementia and tumors of the profound parts of the brain and sometimes with the high pattern of lateral amyotrophic sclerosis. The problem of the clinical varieties of CJD is discussed.

Adult↗
PubMed1990

[Neurologic disorders in insulinoma].

Three cases of insulinoma-related neuropsychic disturbances and literature data are considered. Special emphasis is given to polymorphism of epileptiform syndrome, concomitant disphoric paroxyms and lethargy. A case of a rare syndrome coma vigil is described in the advanced stage of the disease. The discussion covers pathogenetic mechanisms and differential diagnosis.

Adult↗
PubMed1988

[Variants of herpetic encephalomyelitis].

The article presents the results of combined clinico-morphological, virological, and seroimmunological studies in 10 patients aged 16 to 57 years who suffered from acute herpetic encephalomyelitis. The authors have identified 4 clinical syndromes: Landry's ascending paralysis, meningomyelitis, disseminated encephalomyelitis, and brain stem encephalitis. Some aspects of the pathogenesis of herpetic lesions of the central nervous system are discussed.

Acute Disease↗
PubMed1987

[Difficulties in the diagnosis of myasthenia gravis].

The article analyses some specificities in the diagnosis of myasthenia (M) and the clinical characteristics of its course in a series of 62 patients with various forms of the disease. At first presentation M has been diagnosed in 9.7% of the cases. The clinical criteria of the differential diagnosis of M and other diseases are also presented. The role of physical, pharmacological, immunological, and electrophysiological tests at early stages of the disease is assessed.

Adolescent↗
PubMed1986

[Clinical variants of the Tolosa-Hunt syndrome].

On the basis of examination of 25 cases of Tolosa-Hunt syndrome, the author has identified 3 variants of the pathology: classic, with the predominant damage to the oculomotor and to the abducent nerve. It has been shown that immunological assays, CSF examination and carotid angiography are essential for the diagnosis of the syndrome. A differential-diagnostic table is presented. Employment of steroids in the acute period of the disease has yielded good results.

Adult↗