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Biomedical subjects

E Nüssler

Publications and source records attributed to E Nüssler.

8 recordsLinked to original sources

Endometritis caused by Chlamydia trachomatis.

Chlamydia trachomatis was found to be the aetiological agent of endometritis in three women with concomitant signs of salpingitis. All patients developed a significant antibody response to the organism. Chlamydia were recovered from aspirated uterine contents of two patients and darkfield examination of histological sections showed chlamydial inclusions in endometrial cells in one patient. Thus, C trachomatis can be recovered from the endometrium of patients in whom the cervical culture result is negative. In one patient curettage showed endometritis with a characteristic plasma-cell infiltration. The occurrence of chlamydial endometritis may explain why irregular bleeding is a common finding in patients with salpingitis. It also suggests a canalicular spread of chlamydia from the cervix to the Fallopian tubes.

Adolescent↗

[Congenital atrioventricular block--intrauterine diagnosis and neonatal pacemaker treatment].

A complete fetal heart block was diagnosed in 29 weeks gestation by means of 2-dimensional and M-mode echocardiograms and by analyzing the combined Doppler effect of atrial and ventricular movements. Because of increasing fetal ascites and edema, Digoxin treatment is given from 31 weeks gestation until birth. 30 hours postnatal the child develops congestive heart failure which disappeared completely after pacemaker treatment. We stress the importance of early diagnosis with possibility of prenatal treatment and optimal planning of delivery in cooperation between obstetrician and pediatric cardiologist.

Adult↗

Infection with Chlamydia trachomatis, Mycoplasma hominis and Neisseria gonorrhoeae in patients with acute pelvic inflammatory disease.

Of 166 women with acute pelvic inflammatory disease, Mycoplasma hominis was isolated from the cervix of 91 (54.8%), Chlamydia trachomatis was isolated from 37 (22.3%), and Neisseria gonorrhoeae was isolated from nine (5.4%). Of the 91 women from whom M. hominis was recovered, 39 developed a significant change in titer of serum antibodies to the organism within one month after admission. Of the 85 patients from whose cervix M. hominis was not isolated, 11 displayed a significant change in titer of antibody to the organism. A change in the titer of IgG antibodies to C. trachomatis was found in 20 women (54.1%) who had Chlamydia-positive cultures and in 14 (10.9%) whose cultures were negative for Chlamydia. The results of the cultural and serologic studies suggest that M. hominis was associated with pelvic inflammatory disease in approximately one-third of the patients, or in half of those women from whose cervix the organism was isolated. In approximately every fifth woman studied, C. trachomatis seemed to be associated with the pelvic inflammation.

Acute Disease↗