Biomedical subjects

E Noain

Publications and source records attributed to E Noain.

3 recordsLinked to original sources

PubMed2002

Bone metastases from osteosarcoma.

Bony metastases in patients with osteosarcoma are unusual and normally appear late in the course of the disease. We report our experience with eight such patients, four with solitary and four with multiple metastases. Those with solitary metastases were treated as new tumours with neoadjuvant chemotherapy and surgery. Three remain alive with no evidence of disease at 5, 7 and 8 years follow-up respectively. Histology and response to neoadjuvant chemotherapy was similar in both the primary and metastatic lesions and is a predictive factor of outcome. Those with multiple metastases were treated by palliative measures, and none survived. We conclude that resection of solitary metastases from osteosarcoma after neoadjuvant chemotherapy can be curative.

Adolescent↗

PubMedDate not supplied

[Perioperative blood management in primary total knee arthroplasty].

Preoperative autologous blood collection and the reinfusion of postoperative blood salvaged from wound drainage can help to decrease the use of homologous blood transfusion in total knee arthroplasty. We have evaluated 100 primary total knee arthroplasties carried out at the García Orcoyen Hospital between 2001-2003. Eighty-eight point seven percent (88.7%) of available autotransfusion blood packs were employed and the average blood reinfusion from wound drainage was 374 ml. (range: 200-950 ml) when this method was possible. In 69% of cases homologous blood transfusion was not necessary. While other techniques are being developed, we think that autologous blood collection and blood reinfusion from wound drainage are effective in reducing the need for homologous blood transfusion; this is important because of the potential risk of reactions, disease transmission and limited blood bank resources.

Aged↗

PubMedDate not supplied

[Surgical treatment of vertebral metastasis].

Spinal metastases may cause pain and neurologic dysfunction secondary to bone destruction and spinal cord compression. The new oncology therapy have prolonged life expectancy of many patients with different primary tumors. The treatment of metastases is frequently necessary to enhance quality of life. We reviewed 121 patients with spinal metastases of different primary tumors operated between 1982 and 1995. We employed different approach and instrumentation depending on particular case, metastases location and life expectancy. We analysed primary tumor location, spinal pain, neurologic function, pre and post surgical treatment, complications and development. Spinal stabilization and cord decompression gives excellent results for pain relief, neurological improvement and quality of life, always helping to medical treatment of a patient with metastatic disease.

Adolescent↗