PubMed Health⌕ Search

Biomedical subjects

E Nussbaum

Publications and source records attributed to E Nussbaum.

65 records · Page 4Linked to original sources
PubMed1982

Incidence of mitral valve prolapse in adolescent scoliosis and thoracic hypokyphosis.

Seventy-four patients with adolescent scoliosis underwent cardiac examination and M-mode echocardiography to detect the presence of mitral valve prolapse (MVP). Twenty-one (28%) had echocardiographic evidence of MVP, whereas 18 had auscultatory findings of a nonejection click or late systolic murmur. A subset of 41 patients had a family history of scoliosis and 37% had MVP. The incidence of MVP increased to 41% when a first degree relative, such as a sibling, parent, or offspring, had scoliosis. Thirty-six patients with scoliosis had additional thoracic hypokyphosis (straight back) and 13 (36%) had MVP. The incidence of MVP was 48% when the scoliosis and hypokyphosis were hereditary and increased to 53% when a familial history of skeletal abnormality was present. This study indicates a high incidence of MVP in patients with scoliosis and hypokyphosis, especially when the cardiac and skeletal systems may be affected by a generalized soft-tissue defect.

Adolescent↗
PubMed1980

A case of Mycobacterium avium infection: early detection by the auramine-O fluorescent technique.

Infection due to Mycobacterium avium is rare in man and its definitive diagnosis is based upon culture, usually taken from a cervical lesion. The lack of systemic involvement, the negative history for contact with tuberculosis, the normal chest roentgenogram and the fact that Mycobacterium avium complex grows slowly on standard Mycobacterial media, make it difficult to diagnosis. The purpose of this communication is to re-emphasize the possibility of infection by group III Mycobacterium complex in the differential diagnosis of children with cervical lymphadenitis and to describe the important use of Auramine-O fluorescent stain in the early detection of this disease.

Aniline Compounds↗
PubMed1975

The use of sulthiame- in myoclonic epilepsy of childhood and adolescence.

Sulthiame has been used by most investigators in psychomotor seizures, other focal seizures and grand-mal, usually in conjuction with other anticonvulsants. Reports on its use in myoclonic epilepsy and as a sole anti-convulsant are few and inconclusive. The present report presents the results of a study carried out on the use of sulthiame in 54 cases of myoclonic epilepsies originating in infancy, childhood and adolescence. The different types of myoclonic epilepsy are defined. An illustrative case report is included. Results indicated that sulthiame is the drug of choice, often as the sole anti-convulsive agent, in cases of "juvenile myoclonic epilepsy". In the myoclonic encephalopathies of childhood (the so-called "minor motor epilepsy" or Lennox-Gastaut syndrome), which are notoriously refractory to therapy, sulthiame appears to be an efficacious adjunct to currently-used agents, including benzodiazepines, succinimides, dipropyl acetate, steriods and a ketogenic diet.

Adolescent↗
PubMedDate not supplied

The influence of ultrasound on healing tissues.

This paper identifies techniques in ultrasound that influence healing tissues. The importance of appropriate parameters is emphasized. Current literature is reviewed to support the use of ultrasound in specific conditions and different phases of healing. Types of wounds discussed include delayed-closure wounds, deep soft-tissue wounds, tendon and nerve repairs, bone fracture, and burn injury. There is a need for research in ultrasound directly related to hand therapy.

Animals↗
PubMedDate not supplied

Direct determination of tobramycin clearance in patients with mild-to-moderate cystic fibrosis.

Studies performed in patients with cystic fibrosis (CF) have suggested altered pharmacokinetic parameters for aminoglycosides. Specifically, increased plasma clearance (Cl) of aminoglycosides and increased apparent volume of distribution have been noted. In the present study, tobramycin Cl is determined by both serum concentration data and direct renal clearance (Clren). Tobramycin Clren appeared to be directly correlated to the measured creatinine clearance (Clcr) (r = 0.93, p less than 0.01). The tobramycin Cl, by both methods of determination, was not elevated in comparison to the Clcr or expected values for patients without the disease. These results appear to corroborate a recent study in which the renal and plasma Cl of gentamicin was measured in patients with mild-to-moderate CF and were not noted to be elevated. It is suggested that standard doses of tobramycin be used initially in patients with mild-to-moderate CF with dosage adjustment based on serum concentration data to achieve the desired goals.

Adolescent↗