PubMed Health⌕ Search

Biomedical subjects

E O Adekeye

Publications and source records attributed to E O Adekeye.

At least 19 recordsLinked to original sources
PubMed1993

Ameloblastoma: clinical features and management of 315 cases from Kaduna, Nigeria.

This paper reviews 315 cases of ameloblastoma seen and managed at the Oral and Maxillofacial Clinic of Ahmadu Bello University Hospital, Kaduna, Nigeria over a 20-year period. The data collected on age at presentation, sex distribution, clinical presentation and modalities of treatment are analysed and discussed. A male preponderance was found, with peak presentation in the third and fourth decades of life. Few patients presented with mucosal ulceration, while some presented atypically with expansion of either the lingual or buccal cortical plate of the mandible. Resection of the lesion with dento-alveolar bone and preservation of the lower border of the mandible is effective conservative management in patients with an intact lower border. We do not recommend curettage or enucleation because of the frequency of recurrence. One hundred percent success was recorded in the patients rehabilitated using autogenous bone grafts. Where practicable, bone grafting should be done immediately to avoid the common complications of displacement of bony remnants and occlusal disharmony that occur when grafting is delayed.

Adolescent↗
PubMed1990

Paediatric tumours of the jaws in northern Nigeria. Clinical presentation and treatment.

134 cases of paediatric tumours of the jaws in Nigerian children are reviewed. Non-odontogenic tumours and tumours of mesenchymal origin were the commonest. Among malignant disease cases, Burkitt's lymphoma predominated. Late presentation for treatment and gross disfigurement were typical clinical findings. Most of the non-Burkitt malignant lesions had grown to inoperable proportions and the few that were amenable to aggressive surgery responded poorly to treatment.

Adolescent↗
PubMed1988

Mandibular African histoplasmosis: imitation of neoplasia or giant-cell granuloma?

The lesion reported in this article destroyed much of the right side of the mandible in a 14-year-old boy. Clinically, it resembled Burkitt's lymphoma and was initially treated as such. After correct microscopic diagnosis, the mass regressed with the use of intravenous amphotericin B and surgical reduction. The histologic comparison with giant-cell granuloma is considered.

Adolescent↗
PubMed1987

Mesenchymal chondrosarcoma.

2 cases of this rare tumour in Nigerian subjects is described. Clinical features indicated relatively slow but painful growth, aggravated in 1 case by dental extractions. Radical resection was followed by 6-year survival without recurrence or overt metastasis. Microscopic differential diagnosis is discussed.

Adult↗
PubMed1987

Osteosarcoma of the jaws--a series from Kaduna, Nigeria.

15 primary and one metastatic osteosarcoma of the jaw bones in Nigerians are described. The age range was typical of this tumour; most cases were in the mandible. Clinical and radiographic features were often diagnostic but the microscopic appearances were varied and problematical. No metastases were detected and effective surgical treatment depended upon the degree of spread in soft tissue. Inoperable tumours had infiltrated the pharyngeal and tonsillar area. Some resected cases survived for one year or more.

Adolescent↗
PubMed1986

Onchocerciasis of the face and mouth.

Onchocerciasis is characterized by the presence of numerous microfilariae in the skin, by the formation of subcutaneous nodules, and by eye lesions that frequently lead to blindness. The organisms' life cycle and the clinical symptoms and histologic features of the disease are described, together with three case reports from Nigeria. One of the cases involved a rare intraoral lesion.

Adolescent↗
PubMed1986

The versatility of pectoralis major and latissimus dorsi myocutaneous flaps in the reconstruction of cancrum oris defects of children and adolescents.

The application of the recently described myocutaneous flaps in 7 cases of cancrum oris defects is shown and the consistency of the blood supply in children is stressed. The surgical anatomy is mentioned and the use of the flaps in the reconstruction of defects of the cheek, angle of mouth, lips and chin is illustrated. The excellence of the muscle island flap in preventing reankylosis if interposed into new joints in the body of the mandible is emphasised, together with the advantages over the forehead and delto-pectoral flaps when used for the same purpose.

Adolescent↗
PubMed1986

Recurrent ameloblastoma of the maxillo-facial region. Clinical features and treatment.

21 recurrent cases of ameloblastoma in the maxillofacial region in Nigerian subjects are described. These had a typical age, sex and site distribution and characteristic clinical features. Extension of the disease into the cranial vault was seen in one individual but no metastasis was detected at presentation and follow-up review. The effective surgical treatment was en bloc excision with preservation of the lower border of the mandible or radical resection often including adherent soft tissues and skin. Follow-up data were recorded and all the patients were free from the disease for 6 months to 6 years.

Adolescent↗
PubMed1985

Cleft lip and palate in Nigerian children and adults: a comparative study.

A survey of cleft lip and palate in 160 Nigerians is presented. In clefts of the lip alone, there was no sex predilection whereas cleft lip and palate cases showed a slight male preponderance. 119 (74.4%) cases presented below the age of 12 years and 41 (25.6%) cases were first seen above 12 years of age. Only a few cleft lip and palate cases survived to adulthood possibly because of malnutrition combined with the lethal effects of associated congenital abnormalities. This study confirms the view that late primary repair of clefts is less likely to produce impaired growth of the maxilla due to contraction of scar tissue commonly seen in early surgery. The importance of early primary repair is emphasised.

Adult↗
PubMed1985

Osteomyelitis of the jaws: a review of 141 cases.

A survey of 141 cases of osteomyelitis of the jaws is presented. The salient clinical features, the aetiology and treatment of the lesions are described. A high incidence of the disease in the maxilla is noted. Lesions of the maxilla mainly occurred in patients in the first decade of life, whilst those of the mandible affected individuals in the third decade. The possible relationship between infection, blood supply to the jaw bone, and associated debilitating conditions is examined.

Adolescent↗
PubMed1985

Intraoral carcinoma in Nigeria: a review of 137 cases.

Carcinoma of the oral cavity occurring in Africans is poorly documented. Although oral cancer is considered rare in Africa approximately 40 cases of intraoral carcinoma are seen yearly at the Maxillofacial Clinic, Kaduna. This paper reviews 137 cases of malignant disease in the oral cavity and compares the results with previously published literature. Tumours of the major salivary glands and carcinoma that could clearly be shown to originate from the antral mucosa are not included in this series. Lesions of the palate, alveolar ridge and the oral vestibule, all of which appeared to have arisen primarily from the oral mucosa, predominated. A relatively low incidence of carcinoma of the lip and tongue was recorded. The patients were considerably younger than those reported in comparable series from Europe and America.

Adult↗
PubMed1984

Advanced central myxoma of the jaws in Nigeria. Clinical features, treatment and pathogenesis.

18 advanced cases of myxoma of the jaws are described. These had a typical age, sex and site distribution and characteristic clinical and radiographic features. Surgical treatment was radical as benefits large, poorly defined tumours, but there was no evidence that these were aggressive lesions. It is argued that the designation of myxoma as an odontogenic tumour is uncertain though not excluded. Attention is drawn to evidence that many myxomas of the jaws may be examples of myxomatous degeneration in other neoplasms.

Adolescent↗
PubMed1984

Neurofibromatosis of the head and neck: clinical presentation and treatment.

The clinical features of neurofibromatosis of the head and neck in 28 Nigerians are presented. The disease produced varying degrees of cosmetic and functional deformity. Total excision of the lesions, where feasible, with skin grafting, when indicated, gave satisfactory cosmetic and functional results. Incomplete excision was unsatisfactory for all eyelid and other more extensive lesions. Intraoperative bleeding was prominent and postoperative follow-up poor.

Adolescent↗
PubMed1984

Surgical parotid disease in Nigeria: a review of 100 cases.

100 cases of surgical parotid disease are reviewed. Parotid cyst was the commonest non-neoplastic disease, followed by a parotid fistula. 73% of the cases were neoplastic conditions of which approximately 50% were malignant and the patients were much younger than those reported in other series.

Adolescent↗
PubMed1984

Giant frontal sinus mucocoele. Report of two cases.

The giant frontal sinus mucocoele is best approached surgically using a bi-coronal flap to give an ample view of orbital and intra-cranial extensions. The size of the cystic cavity necessitates packing rather than obliteration with autografts. Reconstruction of the frontal bone may be carried out as a secondary procedure.

Female↗
PubMed1983

Ankylosis of the mandible: analysis of 76 cases.

A survey of 76 cases of ankylosis of the mandible in Nigerians is presented. Etiology, clinical features, radiographic findings, anesthetic techniques, surgical treatment, complications, and results are discussed. The operative technique used in each case depended on the site, extent, and type of ankylosis. Five-year follow-up data are reported. Of the 47 patients who were followed, the postoperative interincisal opening was retained in 25 (53.2%), varying degrees of reduction of mouth opening were observed in 17 (36.2%), and ankylosis recurred in five (10.6%). Lack of jaw opening exercise was believed to be responsible for relapse.

Adolescent↗
PubMed1983

Cancrum oris: principles of management and reconstructive surgery.

A survey of 140 cases of cancrum oris in Nigerian Africans is presented. The salient clinical features, the problems of management and the modern approaches to the reconstruction of facial deformities seen in this disease are described. Mainly affected were children under the age of 10 years and the commonest involvement was the full thickness of the cheek. A high incidence of ankylosis was noted and the methods of anaesthesia and surgical correction of ankylosis are examined. The number of patients presenting for reconstruction of facial defects due to cancrum oris appears to be increasing. Preventive measures that may reduce the incidence of the disease are suggested.

Adolescent↗