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Biomedical subjects

E O Amaku

Publications and source records attributed to E O Amaku.

18 recordsLinked to original sources
PubMed1993

The use of intermittent chlorhexidine bladder irrigation in the prevention of post-prostatectomy infective complications.

The efficacy of peri-operative intermittent bladder irrigation with 0.05% chlorhexidine gluconate solution in the prevention of post-prostatectomy infective complications was assessed in men with pre-operative indwelling urinary catheters. Thirty-two consecutive patients undergoing transvesical prostatectomy were randomly allocated to the test group (chlorhexidine irrigation) and control group (saline irrigation). Pre-operatively, intermittent chlorhexidine bladder irrigation achieved sterile urine in only 3 of 13 patients, in the rest bacteriuria persisted. However, the irrigation was able to reduce significantly (P < 0.05) the incidence of intra-operative bacteraemia and severe wound infection. Furthermore, septicaemia was absent and post-operative urinary catheter requirements and hospital stay were shortened. Histology of bladder mucosal biopsies revealed that 0.05% chlorhexidine used on intermittent basis caused no injuries.

Aged↗
PubMed1988

One-stage penile cutaneous island flap repair for hypospadias in circumcized patients.

Routine circumcision of infants, even those with congenital hypospadias, still takes place in some parts of the world. Hypospadias repair in such patients is difficult. We describe our recent experience with a one-stage transverse penile cutaneous island flap repair of congenital hypospadias in 16 circumcized patients. In all patients the graft took. There were only 2 cases of urethrocutaneous fistulae and these were easily closed with rotation flap. Functional and cosmetic results were judged as good in 81% and fair in the rest. There were no repair failures.

Adolescent↗
PubMed1987

Semen features of 596 truly infertile men.

Semen examinations were performed on 596 truly infertile men. The results obtained were compared with those of supposedly infertile men. Our findings indicate that the mean sperm count, mean total sperm per ejaculate, mean percentage motility and morphology of truly infertile males were far lower than past reports suggest. The type of male population studied was identified as the possible source of discrepancy. The data obtained further suggest that the realistic cutoff point between fertile and infertile semen should be a sperm concentration of 10 million/ml, a total sperm per ejaculate of 25 million, percentage motile and well-formed sperms of 40 and 60, respectively.

Adult↗
PubMed1986

Are changing semen parameters a universal phenomenon?

The semen characteristics of 100 fertile indigenous blacks were studied. The mean semen volume was 2.6 ml, sperm density 55 million/ml, motility 61% and well-formed sperm 71%. These figures are comparable to those of similar recent studies in Caucasians but differ significantly from earlier studies. Our data seem to support recent observations that there has been a decline in the sperm density of fertile males in the past 3 decades and that the earlier standards of sperm concentration may be too high for the present.

Adult↗
PubMed1985

The causes of male infertility in 504 consecutive Nigerian patients.

The causes of infertility in 504 men were studied prospectively. The major causes were varicocele (28.8%), infection (20.8%), bilateral testicular failure (15%), idiopathic oligospermia (6.6%), multifactorial (5.6%), cryptorchidism (4%), sexual problems (3.8%) and surgical injury (1.6%). Unilateral testicular torsion and sickle cell disease though of less frequent occurrence were of particular interest because their roles are only now beginning to be realized. Gonadotrophin deficiency was an insignificant cause of subfertility. In spite of the high incidence of infection and past history of urethritis Neisseria gonorrheae was surprisingly not isolated from any patient. Compared with Caucasian studies, the high incidence of infection, and the low incidence of gonadotrophin deficiency are major points of difference.

Adult↗
PubMed1984

Haematuria in Nigerians: a prospective study.

One hundred and ninety Nigerians who presented with haematuria at an out-patient department were fully investigated and treated. There were 135 males and 55 females of mean age 37.8 years. Fifty-eight per cent of them presented over 3 months after onset of symptoms. Haematuria was severe in 27%, painless in 50%, intermittent in 26%. Infection accounted for 22.6%, neoplasms 17.4%, schistosomiasis, 14.2%, trauma 13.7%, benign prostatic hyperplasia 7.9%, calculous disease 7.9% and haemoglobinopathy 2.6%. There was no case of haematuria due to Hb type AS. Aetiology was unknown in 1.6%. Urethrocystoscopy and intravenous urography were the most rewarding investigations. All patients with carcinoma of the bladder presented very late and none survived more than 1 year after diagnosis. Eighty-six per cent of the cases were of non-schistosomal origin and the need for early and thorough investigation of haematuria is stressed.

Adolescent↗
PubMed1977

A study of the effect of anabolic steroids on nitrogen balance.

The study was designed to show if anabolic steroids can improve the protein states of sick Nigerian Children. 5 children in Hospital were used for the study. They did not have any surgical operations immediately preceeding the study. Each child acted as his own control. In two of the five children there was a statistically significant positive nitrogen balance. It was concluded that anabolic steroids may have a place in the management of protein depleted children in Nigeria. A larger number has to be studied to reach a definite conclusion.

Anabolic Agents↗
PubMed1976

Urethral injuries in Lagos.

Good results have been obtained following the treatment of incomplete urethral rupture while the results of complete urethral rupture treated in this hospital by the conventional method have been very poor. This poor result is comparable to those from other centers using similar methods. A review of various treatment methods was undertaken and reasons are given for advocating the method of initial suprapubic cystostomy, followed by delay urethroplasty.

Accidents, Traffic↗
PubMed1976

Nivaquine and urethral pain.

Two patients, one Jewish and the other Nigerian, were investigated for pain in the urethra. They were both fully treated along the usual lines without any change in the pain. The Jewish patient was later found to be sensitive to chloroquine. When ingestion of this drug was discontinued, his urethral pain disappeared after about four months. The Nigerian patient was advised along the same lines when it was found that he too took chloroquine for malarial attacks regularly. He had total symptomatic relief. The probable relationship between chloroquine and urethral pain is discussed.

Adult↗
PubMedDate not supplied

Torsion of testis in Nigerians.

Torsion in a black population is presented. The clinical features are the same as the white counterpart, but the mean age is, however, much higher. There is no bias against any side of testis. Physicians are to blame for the poor salvage rate. Gangrenous testes should not be conserved and early diagnosis and treatment remain the only means of saving torted testis. Prophylactic fixation of contralateral testis is mandatory and must not be postponed. External manual detorsion is not a substitute for surgery and should not remove the sense of emergency. Relevant pathology, the mechanism of torsion and differential diagnosis are discussed.

Adolescent↗