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Biomedical subjects

E O Ogunbodede

Publications and source records attributed to E O Ogunbodede.

29 records · Page 2Linked to original sources

Oral malignancies in Ile-Ife, Nigeria.

Fifty nine patients with histologically confirmed cases of oral malignant neoplasia were included in this study. There was a male preponderance with the male to female ratio being 2.5 to 1.0. The average waiting period before presentation was 8.9 +/- 6.5 months (range: two to 24 months). Squamous cell carcinoma was the predominant variety, 50.8%, of all malignancies recorded. The alveolar ridge and the gingivae were the commonest sites accounting for 40.7% of all cases. Majority of the patients with squamous cell carcinoma, (80.8%), presented with stage IV of this disease. The pattern of oral malignancies in the population studied appears slightly different from earlier observations in Western Europe and Asia. The necessity to strengthen research on the epidemiology of the disease in Nigeria and other African countries is highlighted.

Adolescent↗

Partnership for primary care.

A project for improving primary health care in an underserved rural area of Osun State, Nigeria, involved the creation of a partnership between the local government, the community and a medical college. Joint administrative and technical committees were established, and community mobilization was fostered. The evidence so far indicates that partnership designs can accelerate the development of primary health care in an affordable manner.

Humans↗

Bacteriological studies of dental caries in Ile-Ife, Nigeria.

To determine the relationship between bacterial colonization of tooth surfaces and dental caries, selective agar media-MM10 Sucrose, Rogosa SL and Blood agar were used to isolate bacteria from the scrappings of 60 tooth surfaces of 30 children and young adults. Mean age +/- SD was 13.3 +/- 4.1 (range seven to 19 years). Streptococcus mutans was isolated from 36 surfaces representing 60pc Lactobacillus species from 38 surfaces (68pc), and Actinomyces species from 12 surfaces (20pc). The individual prevalences of these organisms decreased with age. The distribution of bacteria according to surfaces examined showed that the pits and fissures were the main habitat of Streptococcus mutans and Lactobacilli were sensitive to erythromycin. Actinomyces species were 100pc sensitive to Penicillin. All the bacteria species isolated were also found to be 100pc sensitive to Olfoxacin (Tarivid). It is suggested that the use of antibiotics may stop the growth of cariogenic bacteria in individuals and thereby contribute to a decline in the incidence and prevalence of dental caries in the community.

Actinomycosis↗

Oral rehydration therapy--a dental perspective.

Sugar-based Oral Rehydration Therapy (ORT) is still the conventional treatment for diarrhoeal diseases. The WHO/UNICEF, and other groups endorse and actively promote its use for all cases of diarrhoea. Despite the deleterious effects of sugars promotion on dental health, and the incontrovertible role of sugars as the major factor responsible for the present upsurge in dental caries prevalence in the developing countries, the search for an ideal Oral Rehydration Solution (ORS) has so far completely ignored any dental considerations. Of the presently available rehydration solutions, the cereal or food-based solutions offer greater advantages over the sugar based solutions. Further research efforts must be directed at non-sugar based ORT, and funding organisations should give support to researchers and research institutions working to replace sugars with cereal flours, improve food-based ORS, or develop novel approaches to ORT that are based on non-cariogenic ingredients. Policy makers, researchers and health care workers generally must always consider, in addition to other factors, the dental implications of their recommendations on ORT.

Child, Preschool↗

Oral health promotion and health education programmes for Nigeria--policy guidelines.

Nigeria like other developing countries is presently faced with the arduous problem of coping with scarce resources to control existing and increasing oral disease levels. The World Health Organization has emphasized the importance of oral health promotion for initiating successful, effective, preventive oral health programmes. At present however, Nigeria is without formal oral health promotion and health education policies or programmes. In the "National Policy and Strategy to Achieve Health for All Nigerians" (Federal Ministry of Health 1986), no specific mention was made of oral health promotion or oral health education. The present paper therefore proposes definitive policy guidelines that will help in the development of coherent oral health promotion programmes for the country. The approach proposed tackles causes common to a number of chronic diseases and incorporates oral health into general health strategies.

Developing Countries↗

Caring for the people living with HIV/AIDS and AIDS orphans in Osun State: a rapid survey report.

The aim of the study is to obtain the views and opinions of People Living with HIV/AIDS (PLWHAS), community leaders and other stake holders (care providers and AIDS orphans), so as to assess the role of Non-Governmental Organisations in the control of HIV infection with the purpose of making appropriate recommendations for policy formulation on issues related to the health and care of PLWHAs. A qualitative research was carried out using in-depth interview method with a questionnaires as a guide. In all, 12 seropositives, 13 community leaders and 34 AIDS orphans were interviewed. Results indicate that there was a lack of networking between the six Non-Governmental Organisations working in the state in relation to HIV/AID. Also, none of these PLWHAs had concrete plans for the future of their children, though they all expressed some form of anxiety about their children's future. The burden of care of AIDS orphans often fall on the maternal family members. Top on the list of the problem of AIDS orphans was their poor education due to financial difficulties. There is the need for the government to provide, support, encourage and monitor the activities of the Non-Governmental Organisations and network with them so as to maximise the benefits that can be obtained from the role they play in HIV/AIDS management.

Acquired Immunodeficiency Syndrome↗

Helicobacter pylori in the dental plaque and gastric mucosa of dyspeptic Nigerian patients.

BACKGROUND: Presence of helicobacter pylori (H.Pylori) in the dental plaques may be associated with the presence of the same organism in gastric mucosa. OBJECTIVES: To assess and compare the prevalence of H. pylori in dental plaques and gastric mucosa of dyspeptic Nigerians. METHODS: Sixty-six consecutive patients undergoing endoscopy for investigation of dyspepsia were included in the study. A predesigned questionnaire was used to collect information on socio-demographic and other factors. Each patient also had clinical dental examination. Dental plaque scrapping was collected before endoscopy for helicobacter pylori culture, and at endoscopy, two gastric biopsy specimens were taken for culture and histology. RESULTS: The mean age (+/- SD) of the patients was 44.8 (+/- 17.4) years (range 5 to 80 years). The positivity rate of helicobacter pylori in gastric biopsy was 35 of 66 (53.0%) while the same for dental plaque was 46 of 66 (69.7%). The correlation (Spearman's) between gastric mucosa and dental plaque colonization with helicobactor pylori was significant (R = 0.30, P = 0.01). When concordant positivity of gastric biopsy culture and histology was taken as diagnostic, the sensitivity of dental plaque culture was found to be 82.9% and the specificity was 45.2%. CONCLUSIONS: This study revealed that helicobactor pylori has a high prevalence in the dental plaque of the population that we have studied and may therefore be of potential relevance in screening for such infection.

Adolescent↗

Socio-economic factors and dental health in an obstetric population.

The relationship between socio-economic factors and dental health in an Obstetric Nigerian population was studied. The mean gestational age (+/-standard deviation) was 30.16 + 5.45 weeks (range 16-40 weeks). Acquisition of dental education was found to be unrelated to level of education. When the prevalence of dental caries and periodontal disease were considered, the difference between the high, middle and low socio-economic groups were found to be significant (p < 0.05).

Adolescent↗