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Biomedical subjects

E O Tiunder

Publications and source records attributed to E O Tiunder.

12 recordsLinked to original sources

[Reconstruction of the cervical esophagus using a revascularized ileal graft (experimental study)].

The clinic and histomorphology of the revascularized ileum autograft used for the reconstruction and/or replacing the cervical oesophagus in 76 adult mongrel dogs were examined from the 1st to 372nd postoperative days. In 46% of the cases complete recovery of autografts has been established. In 54% of the cases various complications were noticed-very long ischemia, necrosis and spontaneous detachment of the autografts injury of the superficial (endothelial) layer of blood vessels. Thrombosis of blood vessels, tissue haemorrhage, bleeding of the contact areas, wound infections, stenosis of the tubular autografts, unknown cases of abnormalities and mortality could also take place. There are a so-called split or detached contact within the oesophagus and the ileum graft as well as a lowering and enlargement of the villi, atypical crypts, partial replacement of the epithelium columnar cells with goblet cells, inflammatory lymphocytic infiltration of propria and epithelium, high phagocytic activity of the macrophages. The transplant changes can be more rapid if the defect of the cervical oesophagus is filled with a small intestine patch. At the junction of the morphological picture a strong hypo- and atrophy can be observed as well as the destruction and irritation, complete replacement of the columnar cells with mucous cells. In the so-called resorptive contact typical epitheliocytes have been replaced by a polymorphic cell mass. Acute inflammatory infiltration penetrated regionally all over the transplant. The simple columnar epithelium of the ileus transplant has been replaced by the non-keratinized stratified squamous epithelium.

Anastomosis, Surgical↗

[Changes in the tissues of a revascularized transplant of small intestine in the dog under different operating conditions].

Histomorphological changes of revascularized autotransplant were studied in 34 dogs in different conditions of the operation. It was established that revascularization is necessary for transplantation. Organ disintegrates without vascular peduncle. Prolonged operative ischemia (up to 3 hrs) of the transplant causes its essential alternative and destructive changes up to the complete disintegration of part of the villi. Autotransplant of the small intestine preserves tissue and cell composition on the neck for a long period (more than a year) and may be used in replacing operations on the esophagus. However, complete organotypic and tissue restoration of the structure does not occur. Villi disappear, crypt epithelium forms structures resembling terminal regions of cardial glands, simple intestinal epithelium is replaced with the stratified one.

Animals↗

[Complications during puncture of the subclavian vein].

Based on the data of pertinent literature and personal author's material the technic and complications in cannulation of the subclavian vein are analysed. There were 39 complications among 1309 punctures (pleural puncture--in 11, puncture of the subclavian artery-in 20, and thrombophlebitis-in 8). All these complications were not serious and easily liquidated.

Adult↗