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Biomedical subjects

E O Wittig

Publications and source records attributed to E O Wittig.

14 recordsLinked to original sources

Ocular cysticercosis: an epidemiological study.

The objective of the research was to verify the incidence of the ocular form of cysticercosis among the patients who consulted professionals of the field, during the first statistic inventory accomplished in the State of Paraná, Brazil. The 1996 research was performed through a questionnaire sent to all 220 members of Paraná Ophthalmology Association and to the 17 members of Pathology and Cytology Department of the Paraná Medical Association. A pre-stamped envelop for the return of the answers was included in the package. We received 99 answers from ophthalmologists and 10 answers from pathologists. Retrospective and epidemiological research about the incidences of the ocular cysticercosis in the State of Paraná, added to national related published reports, rendered 95 cases probably acquired in Paraná, 71 of the cases were referred in this research and 24 in prior publication. The most frequent localization was vitreous and subretinal, as literature had already pointed out.

Brazil↗

[Greater occipital neuralgia associated with occipital osteolytic lesion. Case report].

The anatomic distribution of the greater occipital nerve during its path permits a close relationship with muscular structures, tendons, vessels and bones. The rupture of this relationship can origin its irritation and headache. We describe an uncommon association between an osteolytic lesion on occipital bone and greater occipital nerve. The patient, female 50, has been presenting headache for two years on the right occipital region spreading to the hemicranic and ipsilateral supraorbital region. The symptoms started spontaneously or by pressure on the trapezius tendon. The pain lasted about 30 minutes, compressive, mild intensity, with no autonomic symptoms and no improvement after the infiltration in the greater occipital nerve. The total improvement of the symptoms after releasing the nerve has allowed us to associate this lesion to the presence of algic symptoms.

Cranial Nerves↗

Ketoconazole in the treatment of cryptococcosis of the central nervous system.

Two patients with cryptococcosis of the CNS were treated with ketoconazole (KTZ), an imidazole derivative with fungistatic properties: they had either failed standard therapy (Amphotericin-B + 5-Fluorocytosine) or suffered intolerable side-effects to it. Both patients were administered KTZ 800 mg/day as monotherapy for six months without interruption and both responded. One month after KTZ therapy was withdrawn, however, a relapse of the infection was seen in one case. Side-effects were minimal during the trial of treatment. KTZ could be a useful drug in some cases of neurocryptococcosis.

Aged↗

Partial aniridia, cerebellar ataxia, and mental deficiency (Gillespie syndrome) in two brothers.

We report on two brothers (in a sibship of three) with partial aniridia, cerebellar ataxia, and moderate mental retardation, with normal G-banded chromosomes. Both present cerebellum hypoplasia; the younger also has congenital pulmonic stenosis. A review of the literature is presented. Cause is unknown, although the possibility of an autosomal recessive gene cannot be ruled out.

Abnormalities, Multiple↗

[Infantile metachromatic leukodystrophy in twins].

The authors report two cases of infantile metachromatic leucodystrophy in monozygotic female twins, born from a second cousin marriage (f = 1/32). The zygosity was determined by means of obstetrics and genetics marker findings.

Child, Preschool↗

[Vogt-Koyanagi syndrome. Report of a case in a pregnant woman].

A 28 year old pregnant woman with Vogt-Koyanagi syndrome is reported. Despite the use of steroid therapy, she became blind. She delivered a boy Apgar 8. The newborn developed a meningoencephalitis in the nursery and died two years later with evidence of cerebral palsy. Correlation between both mother and son disease has not been found.

Adult↗

[Eosinophilic meningomyelitis. Report of a case].

A 31 years old man who developed paraplegia due to a meningomyelitis is reported. Cerebrospinal fluid examination showed 116 white cells with 57% eosinophils. On the 79th day the patient died from pulmonary embolism. On post mortem examination no eosinophilic infiltrations was found. However, a detailed histologic examination was not performed.

Adult↗

[Rubinstein-Taybi syndrome. Report of 2 cases].

Two non-inbred cases of Rubinstein-Taybi syndrome is two non-related sibships with a total of 16 sibs are reported. Clinical features are those classicaly reported. One of the patients (case 1) presents left post-axial polydactily and a history of hydramnion. The cariotype is normal in the other patient (case 2). Nothing is added in this paper as regards the etiology of the syndrome.

Abnormalities, Multiple↗