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Biomedical subjects

E O'Neill

Publications and source records attributed to E O'Neill.

5 recordsLinked to original sources

Asymptomatic carcinoma of the endometrium in a patient on adjunctive tamoxifen therapy for carcinoma of the breast.

A case report of a 70 years old female, on tamoxifen for over five (5) years after a left mastectomy and with lymphadenectomy and radiotherapy in whom an asymptomatic adenocarcinoma of the endometrium is reported. Review of the literature suggests this association, however, definitive proof that tamoxifen causes cancer of endometrium has not been fully accepted. The best study in this regards is the one from Radiohemmet Oncologic Centre from Stockholm, Sweden. Patients with cancer of the breast that have been over two (2) years on tamoxifen should be screened with endovaginal sonograms for thickness of endometrium, thickness over 9mm and possibly over 5mm should be investigated with hysteroscopy and fractional uterine curetage.

Adenocarcinoma

Electrophoresis in the study of diets and digestive rates of seabirds.

Attempts were made to identify unknown gut contents of seabirds by protein analysis using electrophoresis. Standards of undigested fish and squid muscle tissue were compared with muscle tissue at various stages of digestion. Digested mixtures of squid (Loligo reynaudi), Pelagic Goby (Sufflogobius bibarbatus) and Cape Anchovy (Engraulis capensis) did not resemble the undigested standards of each species respectively. Electrophoresis could prove useful in the study of differential digestion rates of seabird prey species.

Animals

Intraocular foreign bodies. Indications for lensectomy and vitrectomy.

This review of the outcome of the conventional management of magnetic foreign bodies shows that, with the exception of the severe open-eye injuries associated with large foriegn bodies, where immediate lensectomy and vitrectomy is required, conventional magnetic extraction should be performed as close to the foreign body as is feasible. It is important to assess posterior segment damage both before and after extraction of the foreign body, as the subsequent management will depend on the presence of vitreous haemorrhage and retinal damage.

Cataract