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Biomedical subjects

E Ohsawa

Publications and source records attributed to E Ohsawa.

9 recordsLinked to original sources
PubMed1997

Acute left ventricular dysfunction and left ventricular thrombus in a patient with cerebral hemorrhage.

A 66-year-old woman was admitted to the hospital with a cerebral hemorrhage. An echocardiogram showed severe left ventricular hypokinesis and a left ventricular thrombus. An electrocardiogram showed ST segment elevation in the precordial leads. The patient's creatine kinase level was elevated. A follow-up echocardiogram performed 1 month after admission showed normalization of left ventricular wall motion and disappearance of the thrombus. The results of thallium myocardial scintigraphy, coronary arteriography, and left ventriculography performed 1 month after admission were normal, and the patient was discharged without clinical sequelae. The cause of the patient's left ventricular dysfunction was believed to be not myocardial infarction or myocarditis, but a massive adrenergic discharge due to the cerebral hemorrhage.

Aged↗
PubMed1989

Extraction of dislocated lenses using vitrectomy techniques.

In fourteen eyes in thirteen patients, dislocated lenses into the vitreous were extracted using the techniques of vitreous surgery. Our surgical techniques of the extraction, as well as the indication and the prognosis, were described in this paper. Techniques of the lens extraction were basically Barraquer's method, but in modified form. Vitrectomy was carried out by open sky approach (in 2 cases) or pars plana approach (in 12 cases). In cases complicated by acute phacolytic uveitis, excellent results were obtained by these surgical techniques after the complete control of inflammation with steroid. Before surgical extraction, intraocular pressure had been elevated over 21 mm Hg in eight cases. But in all these cases intraocular pressure was controlled without medication after surgery. Visual acuity was improved unless chorioretinal atrophy or glaucoma were not accompanied. From these surgical results, it seems to be reasonable to extract surgically the dislocated lens before the eye is severely damaged.

Adult↗
PubMed1984

Pathogenesis of capsular opacification after extracapsular cataract extraction. An animal model.

Opacification of the posterior capsule is the most common post-operative complication of extracapsular cataract surgery. We studied the sequential changes in the posterior capsule of the aphakic cat and monkey after extracapsular surgery using light microscopy, scanning electron microscopy, and transmission electron microscopy. In the cat, but not the monkey, there was proliferation of a pigment-containing membrane arising from the iris root and ciliary body, and extending onto the residual lens capsule. In both animals there was transformation of residual lens epithelial cells to fibroblasts which contain contractile elements (myofibroblasts) and are associated with collagen deposition. In the cat, pigment epithelial cells from the iris or ciliary body, as well as the transformed lens epithelial cells, contributed to late opacification of the posterior capsule.

Animals↗
PubMed1982

Scanning electron microscopic observation of glial cells following xenon arc photocoagulation.

The retinal tear produced in rabbits by aspirating the vitreous body was treated by means of photocoagulation, and its time-course changes were observed under a scanning electron microscope. Four weeks after photocoagulation, the surface of the retina surrounding the tear began to swell glial cells, that protruded with the lapse of time. About 6 weeks after photocoagulation, the glial cells perforated the internal limiting membrane of the retina and came out its surface, so that the glial cell processes and the cell perikaryon could be clearly observed morphologically. The findings showed that the glial cells are fibrous astrocytes. Seven weeks after photocoagulation, glial cells proliferated even in the retinal tear and, furthermore, glial cells in the space between the retinal tear and the retina surrounding it joined together by intertwining their processes to form a network, which seemed to play a certain role in repairing the tear.

Animals↗
PubMed1982

In vitro potentiation of cephalosporins by alafosfalin against urinary tract bacteria.

Potentiating activity of alafosfalin was examined in detail with 8 cephalosporins and mecillinam against 164 urinary bacteria representing 8 genera. Alafosfalin was generally comparable in activity to cefamandole and mecillinam but superior to other cephalosporins tested. When the minimal fractional inhibitory concentration indices were compared, synergism was observed with all of the beta-lactams tested for all species except Streptococcus faecalis. Marked synergism was observed with Escherichia coli, Citrobacter, and enterobacter and, among the drugs tested, with cefamandole and mecillinam. Although alafosfalin is inactive against Pseudomonas aeruginosa, potentiation was seen with cefsulodin. The most favorable combination ratio of alafosfalin/cephalosporin to elicit potentiation was determined for each species and occurred in a rather narrow range of combinations (1:4 to 4:1 in general).

Alanine↗
PubMedDate not supplied

A minimum essential structure of LN-3 elicitor activity in bean cotyledons.

A great deal of an elicitor-active oligosaccharide (1.47 g) was obtained from 40 g of polysaccharide laminaran with the guidance of elicitor activity in the bean cotyledon assay. Physicochemical means suggested that the oligosaccharide was a beta-1,3- and beta-1,6-linked triglucoside. This was a partial structure of LN-3, having elicitor activity to alfalfa and bean. The triglucoside exhibited a specific elicitor activity to bean, not to alfalfa and pea. The highly digested hydrolysate containing monomer and dimers as major components did not show elicitor activity in the bean cotyledon assay. The structural feature was essential for elicitation of phytoalexin accumulation in bean cotyledons. These results suggested that this triglucoside had a specific elicitor activity and a minimum elicitor-active entity to bean cotyledons.

Carbohydrate Conformation↗