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Biomedical subjects

E P Kudriavtseva

Publications and source records attributed to E P Kudriavtseva.

4 recordsLinked to original sources
PubMed2006

[Bioelectric brain activity in patients with neurotic disorders].

Seventy-three patients with neurotic disorders, aged 14-35 years, and 33 healthy controls have been examined using electroencephalographic method with spectral analysis of EEG, which has been conducted on the Brain Surfing system by the algorithm of direct Fourier transformation. The patients had changes of brain electric activity manifesting as insufficiency of thalamo-cortical synchronizing systems that caused an excessive activating effect of reticular formation on the cortex realized through extrathalamic reticular cortical and septo-hippocampal activation paths. Determinative in electrophysiological brain organization was the theta-rhythm, a marker of excessive emotional and autonomic activation, which directly correlated with an extent of personality accentuation and severity of neurotic state.

Adolescent↗
PubMed2001

[Parietal theta rhythms in carbamazepine therapy of children with epilepsy].

UNLABELLED: Regional bioelectrical activity changes presenting as prolonged or periodic inhibition at the central parietal leads in theta rhythm (PT) are regarded in some studies as congenital predisposition to epilepsy. The study estimates a carbamazepine (CBM) therapy efficacy in children with epilepsy with- or without PT. To study the prognosis in CBM therapy, 119 patients, 63 with PT (group 1) and 56--without PT (group 2) have been retrospectively examined. Patients with the presence of generalized spike-and-wave activity (SWA) before CBM treatment have been excluded from the study. Despite the insignificant between-group differences of clinical and EEG-data before the therapy beginning, the CBM response was much worse in the group 1: a marked effect was found in 14 (22%) patients, in 41 (65%) the effect was mild or absent at all, and in 8 (13%) a disease course worsening was detected. In group 2 a good effect was in 42 (75%) patients, no effect was detected in 14 (25%) patients and none of the patients was worse. Correlations between SWA appearance and inadequate CBM action, as well as between improvement/worsening absence of EEG and favorable prognosis during therapy have been found. CONCLUSIONS: Carbamazepine efficacy in the children with epilepsy is significantly lower in the presence of parietal theta rhythm. PT is likely to be a liability factor for SWA appearance during CBM therapy.

Adolescent↗
PubMed1998

[Changes in evoked slow cerebral potential (contingent-negative variation) in epilepsy].

Contingent negative variation (CNV) was examined in 14 epileptic patients (5 with generalized and 9 with partial fits) both before and after 24 hours of sleep deprivation. Background CNV indices differed significantly by higher amplitudes of nearly all CNV components from the ones of healthy individuals. Amplitudes of postimperative negative waves (PINW) and general waves differed most of all. After sleep deprivation there was an PINW increase as well as the tendency to the late CNV component amplitude's increase. Elevation of CNV amplitudes after sleep deprivation was more pronounced in patients in which the deprivation provoked development of epileptic fits in comparison with patients which endured sleep deprivation rather favourably. The changes revealed in CNV components of the patients with epilepsy were considered in terms of disorders in regulatory mechanisms at the level of apical dendrites of cortical neurons' excitation.

Adult↗