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Biomedical subjects

E P Turk

Publications and source records attributed to E P Turk.

4 recordsLinked to original sources

The histological features of splenosis.

This study presents a detailed histological analysis of two cases of splenosis, including one of the largest nodules to be reported. Splenosis may exhibit red and white pulp that appears histologically and immunohistochemically normal by routine methods, and a well-developed capsule and trabeculae may form. The capsule may be thicker than in the normal spleen but is otherwise indistinguishable and may contain fibrous, elastic and smooth muscle elements. These findings are in contrast to previously published works which have described poorly-developed white pulp, capsule and trabeculae in splenosis. The histological pattern may depend on the blood supply to the autotransplanted splenic tissue in the early days after implantation. The close resemblance that splenosis may show to an accessory spleen suggests that histological examination may have a limited role in the distinction between these two conditions.

Adult↗

Acute renal failure and infectious mononucleosis.

Renal failure is a rare complication of infectious mononucleosis, and is usually due to acute interstitial nephritis. Outcome has been variable with spontaneous recovery, death, and chronic renal failure being described. Only two patients have been reported as requiring dialysis. In some cases the aetiology of the interstitial nephritis has been open to doubt and may have been drug-induced. The case of a patient with acute renal failure associated with infectious mononucleosis and in whom interstitial nephritis appears to have been totally related to the underlying disease is described. There was an excellent response to treatment with high doses of methyl prednisolone given intravenously.

Acute Kidney Injury↗

Pulmonary schistosomiasis.

Two cases are reported of the incidental finding of pulmonary schistosomiasis in the victims of a fatal aircraft accident. The presence of this disease had no bearing on the causation of the accident, but it gives insight into the potential hazards of dissemination of diseases by travellers. The finding also emphasises the value of routine postmortems and histology in all aircraft accident victims.

Child↗

The value of postmortem examination of passengers in fatal aviation accidents.

Annex 13 to the Convention on International Civil Aviation recommens that the state conducting the inquiry into a fatal aviation accident should encourage internal autopsy by an aviation pathologist of those killed. Many countries recognise the value of such examinations on operating crew, but require the examination of passengers merely as aids to identification and to the investigation of the cause of death. This paper attempts to correct this misconception and to demonstrate the importance of examining passengers as completely as possible. The reasons for doing this can be divided into three broad groups. The first concerns accident reconstruction and involves a careful analysis of the injury patterns sustained by the passengers. The second is concerned with the evaluation of the safety equipment provided for passengers' use. The third deals with the multitude of medico-legal problems, both civil and criminal, that inevitably arise after a fatal accident.

Accidents, Aviation↗