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E Palócz

Publications and source records attributed to E Palócz.

3 recordsLinked to original sources
PubMed1993

Comparative examination of Adalat and Cordaflex in anti-ischaemic therapy.

The efficacy of Cordaflex (EGIS) and Adalat (Bayer), both containing 10 mg nifedipine, has been examined in ischaemic cardiopathic patients. The fifteen ischaemic cardiopathic patients were treated with identical doses of Cordaflex and Adalat, simultaneously with unchanged nitrate and beta-blocker therapy. The patients received 30-80-mg identical nifedipine doses daily for 1 week each. In 13 patients change was observed neither in the weekly nitroglycerin consumption nor in the time or intensity of silent and active ischaemic periods registered with 24-hour ECG monitoring. Significant change was observed in one patient during Cordaflex administration, in another patient during Adalat therapy. However, these changes were attributed either to the progression of, or to the spontaneous improvement in the primary disease. Considering the effect influencing blood pressure and heart rate, and one side-effect, there was no difference between the two products. The anti-ischaemic effect of Cordaflex and Adalat was found to be identical.

Adrenergic beta-Antagonists↗
PubMed1989

Captopril (Tensiomin) in the treatment of chronic heart failure of ischaemic heart disease patients.

The authors used Captopril (Tensiomin, Egis Pharmaceuticals, Budapest) therapy in seven patients suffering from chronic heart failure of ischaemic etiology. As controls, seven patients with dilated cardiomyopathy were involved in the study. All 14 patients received digitalis, diuretic, and isosorbide dinitrate therapy but their condition aggrevated in spite of the therapy. The above-mentioned therapy was completed with daily 3 x 12.5-mg or 3 x 25-mg oral Captopril doses. Significant improvement proved by chest X-ray, echocardiography, and clinical data was observed in four of the ischaemic heart disease patients and three of the dilated cardiomyopathic patients. In other two patients each the improvement was temporary, after 6 weeks of therapy deterioration of the disease was observed. Notable change was not observed in response to Captopril in one ischaemic and two primary cardiomyopathic patients. Tensiomin may be considered as one of the drugs of primary importance in the treatment of chronic congestive heart failure.

Adult↗