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Biomedical subjects

E Platonova

Publications and source records attributed to E Platonova.

11 recordsLinked to original sources
PubMed1980

[Clinical and functional study on the evolution of diabetic macroangiopathy].

Forty seven patients and 26 healthy subjects controls were followed up in the course of 8 years. Twenty fine from the diabetic patients were without vaso-active medication and 22--treated with various vaso-active drugs (Hydrosarpan 711, Eleparon, Radecol, Padutin, Trental, etc.). The clinical approach was made use of for the periodical controls as well as non invasive methods with 60 channel ECG "Hellige" apparatus, electronic device "Dopton" oscillograph "Gesenius--Keller", double rheograph "Shulfrid", tastotherm P-60 "Braun", contact skin thermography according to Trikoir. A complex of functional tests was also applied. A statistically significant decrease (P < 0,001) ws established to develop in 83,9 per cent of the diabetic patients without vaso-active medication versus 47.6 per cent of those with medication and 11.5 per cent in the controls. The lesions of the lower limbs get significantly ahead (P < 0.05) of the coronary lesions both in frequency and evolution. The existing so far pessimism about the therapeutic effect of diabetic macroangiopathy is admitted not to be fully reasonable.

Adolescent↗
PubMed1976

[Itsenko-Cusing syndrome in hypohyseal adenoma].

A case observed at the Insitute of Endocrinology, Gerontology, and Geriatry is reported with Icenko--Cushing syndrome developed in consequence of hypophyseal adenoma. The telegammatherapy (total focal dose 4760 rads) carried out in the course of one year led to a complete regression of the developed alterations-- elimination of the redistribution of fats, restoration of the face normal colour and oval, nails and hair normalization as well as of cortisolemia and decrease in the osteoporosis degree with consolidation of the pathological fractures. Blood pressure (without hypotensive treatment) within normal values--140/90.

Adenoma↗
PubMed1975

Rheographic estimation of peripheral diabetic angiopathy.

Longitudinal rheography was used for investigation of 294 diabetics and 176 healthy controls aged 3-82 years. It was found that the vascular lesions in the lower extremities in diabetics are bilaterally similar, and that they are 3-14 times more frequent in comparison with nondiabetic controls. Whereas the diabetics are certainly threatened by severe vascular obliteration with advanced age, the same is not necessary for the nondiabetics. Lighter vascular lesions were found even in diabetic children under 5 years of age. A conclusion is reached that rheography is a reliable method for investigation of vascular lesions in diabetic patients.

Adolescent↗
PubMed1975

[Observation of a male patient with the empty sella turcica syndrome].

One case with secondary developed syndrome of sell turcica is described, after hypophysis radiation on the occasion of acromegaly. Of special interest is the preserved tropic hypophysis secretion with a clinical picture of hypopituitarism (secondary developed hypogonadism, hypothyroidism and hypocorticism) as well as the combination with another brain neoplasm--astrocytoma.

Autopsy↗
PubMedDate not supplied

[The functional state of the hypothalamo-hypophyseal system in tumors of the pituitary and diencephalic area].

A study was made of 38 persons, including 25--with acromegaly, 5--with chromophobic adenomas of the hypophysis, 3--with diencephalic tumours and 5 healthy individuals. STH, TTH and ACTH were determined in the blood plasma with the aid of radioimmunological methods under basic conditions and L-DOPA loading (10 mg per 1 kg of weight) with insulin (0.10 U/kg). There was an increase in the plasma content of STH, TTH and ACTH with a maximum 60 min after the administration of L-DOPA. In the patients with acromegaly STH increased considerably, and in cases with chromophobic adenomas and diencephalic tumours--less. ACTH level was also elevated. STH and ACTH level rose after insulin hypoglycemia. Possible mechanisms of a stimulating action of L-DOPA and insulin are discussed.

Acromegaly↗