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Biomedical subjects

E Ploeşteanu

Publications and source records attributed to E Ploeşteanu.

4 recordsLinked to original sources

Studies concerning the ergogenic value of Cantamega-2000 supply in top junior cyclists.

The effects of vitamins, minerals and amino acids supply were recorded in a group of 20 top junior cyclists by a double blind, controlled trial for four weeks. Ten top junior cyclists received orally 1 tablet Cantamega-2000, daily at breakfast, as supplement of food, for four weeks, while other 10 junior cyclists (members of the same team), having the same program of training (2 hours daily on road, about 80 km), the same controlled food and being under medical supervision, received 2 tablets of Polivitaminizant S (Romanian product which contains 9 vitamins), also at breakfast. Significant and favourable changes were recorded in the group treated by Cantamega-2000 (vitamins, minerals, amino acids, selenium and others) for the total calcium, magnesium, haemoglobin and proteins in serum, comparing to the control group, which received Polivitaminizant S. At the same time we noticed a faster metabolic (urine mucoproteins) and fatigue recovery after Cantamega-2000 supply. Serum cholesterol and GPT did not change significantly in both groups. Based on these data, the authors recommend a supply of vitamins, minerals, amino acids and selenium ratio, by 1 tablet Cantamega-2000, daily at breakfast, including the days of competitions, for cyclists, in order to improve the biological potential of the body and accelerate recovery after exercise.

Adolescent↗

Studies regarding the antioxidant effects of selenium on top swimmers.

The authors performed another controlled trial in 33 top swimmers (16 girls and 17 boys) in order to make evident some acute and chronic effects (antioxidant) of selenium. Lipid peroxides (MDA-malondialdehyde), nonproteic--SH (essential glutathione) in the serum and blood lactate had been recorded initially on basal conditions and after 2 h endurance training (swimming) accompanied by a per oral administration of 150 micrograms selenium (respectively placebo); one week later we applied the cross-over method. In another trial we continued the treatment with 100 micrograms selenium daily for 14 days (n = 9), respectively placebo (n = 7) and then we applied the crossover method for another 14 days. The above biochemical parameters were recorded initially at rest, under basal conditions, after 14 days of treatment and again after 14 days of treatment, when crossing-over. No significant changes were noticed after a single dose + 2 h hard training, both under selenium and placebo treatment and also when the cross-over method was applied. Fourteen days of selenium treatment induced significant changes of lipid peroxides (especially when the subjects came after placebo) and nonproteic--SH, compared to placebo, changes which support the idea of some antioxidant effects of selenium which might be useful in endurance athletes.

Administration, Oral↗

Studies concerning the ergogenic value of protein supply and 1-carnitine in elite junior cyclists.

The effects of protein supply and 1-carnitine were recorded in a group of junior elite cyclists by a prospective double blind placebo controlled trial for six weeks (Refit milk powder containing about 90% proteins and 5% mineral salts-Ca, P, K, Na and 1-carnitine tablets). Seven top junior cyclists received orally 1 g protein/kg.d as supplement of food for six weeks and 2 g 1-carnitine, also orally, per day, 10 days before an important competition; other 7 cyclists received the same regimen as placebo. Significant and favourable changes were recorded in the treated group for the strength index, lean body mass, fat mass, TWP (total work-kgm, performed on cycloergometer 1', serum proteins, serum Hb, serum calcium) changes which did not appear in the control group. Serum cholesterol, creatinine, thymol test and serum GPT did not change significantly in either group. All athletes were under medical supervision, had a controlled training programme and food and received daily only vitamins and mineral salts. The treated group supported better the stress-induced efforts and obtained higher performances in the international competition which took place at the end of the experiment. Based on these data the authors recommend a supply of protein ratio up to 3.2 g/kg.d, six weeks before competition and 2 g 1-carnitine daily, also orally, 10 to 14 days before competition, including the day of competition, for cyclists, in order to improve the biological potential of the body.

Bicycling↗

Studies on selenium in top athletes.

The authors performed a controlled trial in 18 top athletes (9 weight lifters and 9 rowers, girls) in order to make evident some chronic and acute effects (antioxidant) of selenium. Nonprotein--SH (essential glutathione), lipid peroxides (MDA-malondialdehyde), glucose-6-phosphate dehydrogenases (G-6-PDH) and fructose-1,6-diphosphate aldolase in serum, have been recorded initially on basal conditions, after 3 weeks of treatment (100 micrograms/day selenium or placebo) and again after 3 weeks of treatment, also on basal conditions, when crossing over the groups (between a free interval of 10 days). In another trial we registered these parameters on basal conditions and after two hours of hard training accompanied by a per oral administration of 150 micrograms selenium (respectively placebo). The results show significant changes under selenium treatment of the peroxides, G-6-PDH and light changes, not significant of the nonprotein--SH, changes which could suggest an antioxidant effect of this element.

Adolescent↗